Cyanine5.5 DBCO

Cyanine5.5 Cycloalkynes Copper-free click chemistry
Cat. # Quantity Price Lead time
A70F0 1 mg $125 in stock
B70F0 5 mg $260 in stock
C70F0 10 mg $325 in stock
D70F0 25 mg $510 in stock
E70F0 50 mg $895 in stock
F70F0 100 mg $1490 in stock
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Strain promoted alkyne azide cycloaddition (SPAAC) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAC click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

Cyanine5.5 DBCO, F70F0
Cyanine5.5 DBCO, F70F0
Cyanine5.5 DBCO, F70F0
Structure of Cyanine5.5 DBCO
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Absorption and emission spectra of Cyanine5.5

Absorption and emission spectra of Cyanine5.5

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Cyanine5.5 alkyne is a NIR (near infrared) dye azide for copper-catalyzed сlick сhemistry.
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Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye. An analog of Cy5®; free carboxylic acid.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 882.5
Molecular weight: 1029.14
CAS number: 2643308-61-4
Molecular formula: C61H63N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2

Product citations

  1. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science, 2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  2. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry, 2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018
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