Crosslinking in Applications
Bifunctional crosslinkers are molecules that contain two functional groups, either identical, or different, for the synthesis of conjugates of biomolecules.
Lumiprobe offers a range of bifunctional crosslinker molecules that contain various terminal reactive groups flanking different linkers, including short alkyls, and longer polyethylene glycols (PEGs).
3-Azidopropanol
Azidopropanol is a short bifunctional linker compound with azide and hydroxyl functional groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1419-1g | 1 g | $285 | in stock | |
1419-5g | 5 g | $650 | in stock |
3-Azidopropylamine
Water-soluble, bifunctional short crosslinker with amino and azide groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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58-1g | 1 g | $145 | in stock | |
58-5g | 5 g | $490 | in stock |
3-Azidopropylamine hydrochloride
A bifunctional short linker with amino and azido groups. A solid, chemically stable hydrochloride form of azidopropylamine. This product is ideal as an azidopropylamine bulk for applications when a large amount of reagent is needed.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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4003-50g | 50 g | $5990 | in stock |
3-Maleimidopropionic acid NHS-ester
Bifunctional crosslinker with an amine-reactive succinimidyl ester and a thiol-reactive maleimide group.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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3419-500mg | 500 mg | $110 | in stock |
Alkyne hydrazide
Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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41770 | 25 mg | $110 | in stock | |
51770 | 50 mg | $195 | in stock | |
61770 | 100 mg | $290 | in stock |
Alkyne maleimide
Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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41780 | 25 mg | $95 | in stock | |
51780 | 50 mg | $175 | in stock | |
61780 | 100 mg | $200 | in stock |
Alkyne-PEG2-amine
Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2065-1g | 1 g | $120 | in stock | |
2065-5g | 5 g | $350 | in stock | |
2065-25g | 25 g | please inquire | 5 days |
Alkyne-PEG2-carboxylic acid
Bifunctional diethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2155-1g | 1 g | $380 | in stock |
Alkyne-PEG2-iodide
Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
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2136-1g | 1 g | $450 | in stock |
Alkyne-PEG2-NHS ester
Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on diethyleneglycol (PEG2).
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2219-1g | 1 g | $450 | in stock | |
2219-5g | 5 g | $980 | in stock |
Alkyne-PEG3-amine
Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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425-1g | 1 g | $195 | in stock | |
425-5g | 5 g | $580 | in stock | |
425-25g | 25 g | please inquire | in stock |
Alkyne-PEG3-carboxylic acid
Bifunctional triethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1743-1g | 1 g | $490 | in stock | |
1743-5g | 5 g | $980 | in stock | |
1743-25g | 25 g | please inquire | in stock |
Alkyne-PEG3-maleimide
Bifunctional spacer with alkyne and maleimide groups for conjugation of biomolecules.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2344-100mg | 100 mg | $140 | in stock | |
2344-1g | 1 g | $530 | in stock |
Alkyne-PEG3-NHS ester
Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2298-1g | 1 g | $490 | in stock | |
2298-5g | 5 g | $980 | in stock |
Alkyne-PEG3-OH
Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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418-1g | 1 g | $95 | in stock | |
418-5g | 5 g | $280 | in stock | |
418-25g | 25 g | please inquire | in stock |
Alkyne-PEG4-amine
A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2025-100mg | 100 mg | $95 | in stock | |
2025-1g | 1 g | $390 | in stock |
Alkyne-PEG4-carboxylic acid
Bifunctional tetraethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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2187-1g | 1 g | $380 | in stock |
Alkyne-PEG4-iodide
Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
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2188-1g | 1 g | $450 | in stock |
Alkyne-PEG4-maleimide
Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2002-100mg | 100 mg | $150 | in stock | |
2002-1g | 1 g | $590 | in stock |
Alkyne-PEG4-NHS ester
Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on tetraethyleneglycol (PEG4).
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2409-100mg | 100 mg | $250 | in stock | |
2409-1g | 1 g | $790 | in stock |
Amine-PEG2-carboxylic acid
Hydrophilic PEG2-linker with a terminal amino group and a carboxyl group.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2817-250mg | 250 mg | $90 | in stock |
Amine-PEG3-carboxylic acid
Hydrophilic PEG3-linker with a terminal amino group and a carboxyl group.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2616-250mg | 250 mg | $90 | in stock | |
2616-1g | 1 g | $230 | in stock | |
2616-2g | 2 g | $390 | in stock | |
2616-5g | 5 g | $690 | in stock |
Amine-PEG3-OH
Bifunctional PEG3 derivative with amine and hydroxyl groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2774-1g | 1 g | $190 | in stock | |
2774-5g | 5 g | $490 | in stock | |
2774-25g | 25 g | please inquire | in stock |
Amine-PEG4-carboxylic acid
Hydrophilic PEG4-linker with a terminal amino group and a carboxyl group.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2722-250mg | 250 mg | $110 | in stock | |
2722-1g | 1 g | $249 | in stock |
Amine-PEG4-OH
A hydrophilic tetraethylene glycol derivative with terminal amino and hydroxyl groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2473-1g | 1 g | $190 | in stock | |
2473-5g | 5 g | $490 | in stock | |
2473-25g | 25 g | please inquire | in stock |
Amine-PEG6-OH
A hydrophilic hexaethylene glycol derivative with terminal amino and hydroxyl groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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3053-1g | 1 g | $219 | in stock |
ATFB SE (N-Succinimidyl 4-Azidotetrafluorobenzoate)
N-Succinimidyl 4-Azidotetrafluorobenzoate (ATFB SE, ATFB-OSu) is a photo-activatable linker used as a versatile labeling agent for investigating biological receptors.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2574-250mg | 250 mg | $146 | in stock | |
2574-1g | 1 g | $420 | in stock |
Azide-PEG2-amine
A diethylene glycol (PEG2) linker with azide and amino groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2581-1g | 1 g | $110 | in stock | |
2581-5g | 5 g | $260 | in stock | |
2581-10g | 10 g | $390 | in stock |
Azide-PEG2-carboxylic acid
Bifunctional diethylene glycol with terminal carboxyl and azido groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2816-250mg | 250 mg | $230 $199 | in stock |
Azide-PEG2-iodide
A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2636-250mg | 250 mg | $290 | in stock | |
2636-500mg | 500 mg | $430 | in stock | |
2636-1g | 1 g | please inquire | in stock |
Azide-PEG3-amine
A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)
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Cat. # | Quantity | Price | Lead time | Buy this product |
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218-1g | 1 g | $95 | in stock | |
218-5g | 5 g | $280 | in stock | |
218-25g | 25 g | please inquire | in stock |
Azide-PEG3-azide
Triethylene glycol diazide is a bifunctional crosslinker bearing two azide groups. Suitable for click chemistry.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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207-1g | 1 g | $95 | in stock | |
207-5g | 5 g | $390 | in stock | |
207-25g | 25 g | please inquire | in stock |
Azide-PEG3-carboxylic acid
Bifunctional triethylene glycol with terminal carboxyl and azido groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2558-1g | 1 g | $265 | in stock | |
2558-5g | 5 g | $950 | in stock |
Azide-PEG3-chloride
Azide-PEG3-chloride contains a reactive halogen atom and an azide group for click chemistry reaction. It can also serve as a protected amine group equivalent.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2106-1g | 1 g | $490 | in stock |
Azide-PEG3-iodide
Azide-PEG3-iodide is a bifunctional linker with a highly reactive alkylative halogen functional group and an azido group for click chemistry or Staudinger ligation.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2163-1g | 1 g | $290 | in stock | |
2163-5g | 5 g | $590 | in stock | |
2163-25g | 25 g | please inquire | in stock |
Azide-PEG3-OH
Azide-PEG3-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG3 linker in between.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1742-1g | 1 g | $90 | in stock |
Azide-PEG3-tetrazine
A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2798-250mg | 250 mg | $549 | in stock |
Azide-PEG4-amine
PEG4 amine azide is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1868-1g | 1 g | $90 | in stock | |
1868-5g | 5 g | $250 | in stock | |
1868-25g | 25 g | please inquire | in stock |
Azide-PEG4-azide
PEG4 diazide is a homobifunctional linker with two azide groups. It can be used for the synthesis of dimeric molecules with a hydrophilic core by click chemistry.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1865-1g | 1 g | $90 | in stock | |
1865-5g | 5 g | $250 | in stock | |
1865-25g | 25 g | $950 | in stock |
Azide-PEG4-carboxylic acid
Bifunctional tetraethylene glycol with terminal carboxyl and azido groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2723-250mg | 250 mg | $134 | 21 days | |
2723-1g | 1 g | $299 | 21 days |
Azide-PEG4-hydrazide
A bifunctional reagent containing the azide group and hydrazide function. It reacts with aldehydes and ketones. The azide group can then be coupled with various alkynes via CuAAC reaction.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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4697-100mg | 100 mg | $248 | in stock | |
4697-500mg | 500 mg | $791 | in stock |
Azide-PEG4-OH
Azide-PEG4-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG4 linker in between.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2472-1g | 1 g | $140 | in stock |
Azide-PEG6-NHS ester
A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).
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Cat. # | Quantity | Price | Lead time | Buy this product |
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3692-250mg | 250 mg | $325 | in stock | |
3692-1g | 1 g | $539 | in stock |
Azide-PEG6-OH
Water-soluble heterobifunctional crosslinker with a primary hydroxyl group, alkyne-reactive azide group, and a PEG6 hydrophilic linker.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2989-500mg | 500 mg | $209 | in stock | |
2989-1g | 1 g | $319 | in stock |
Azidobutyric acid NHS ester
Activated NHS ester for azido-labeling of peptides and proteins.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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53720 | 50 mg | $110 | in stock | |
63720 | 100 mg | $210 | in stock | |
73720 | 1 g | $950 | in stock | |
83720 | 5 g | please inquire | in stock |
Biotin-PEG3-OH
Bifunctional triethyleneglycol linker with biotin and hydroxyl moieties.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2784-100mg | 100 mg | $110 | in stock | |
2784-1g | 1 g | $298 | in stock |
Cholesterol-PEG4-azide
Cholesterol derivative with azide group for сlick chemistry conjugation.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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4340-100mg | 100 mg | $165 | in stock | |
4340-500mg | 500 mg | $447 | in stock |
Cyanine3-PEG4-BCN (exo)
Cyanine3-PEG4-BCN is an ethylene glycol separated linker for the azido-modified molecules for copper-free click conjugation.
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---|---|---|---|---|
NO items of this product available in stock but you can submit request for bulk. |
Cyanine7 dicarboxylic acid
Cyanine7 dicarboxylic acid is a bifunctional dye molecule possessing two carboxylic acid groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1512-1mg | 1 mg | $125 | in stock | |
1512-5mg | 5 mg | $260 | in stock | |
1512-25mg | 25 mg | $510 | in stock | |
1512-50mg | 50 mg | $895 | in stock | |
1512-100mg | 100 mg | $1490 | in stock |
DBCO-amine trifluoroacetate
Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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1280-100mg | 100 mg | $218 | in stock | |
1280-500mg | 500 mg | $678 | in stock | |
1280-1g | 1 g | $1200 $1018 | in stock |
DBCO-NHS ester
Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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34720 | 10 mg | $80 | in stock | |
44720 | 25 mg | $110 | in stock | |
54720 | 50 mg | $135 | 5 days | |
64720 | 100 mg | $210 $178 | in stock | |
94720 | 1 g | $1000 $970 | in stock | |
K4720 | 5 g | $3570 $2990 | in stock |
DBCO-PEG6-NHS ester
A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).
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Cat. # | Quantity | Price | Lead time | Buy this product |
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3664-50mg | 50 mg | $247 | in stock | |
3664-100mg | 100 mg | $449 | in stock | |
3664-1g | 1 g | $3490 | 5 days |
DBCO-STP ester
Activated ester for modification of proteins/antibodies/peptides followed by introduction into copper-free click chemistry reaction.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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2584-10mg | 10 mg | $90 | in stock | |
2584-25mg | 25 mg | $180 | in stock | |
2584-100mg | 100 mg | $450 | in stock | |
2584-500mg | 500 mg | $1700 | 5 days | |
2584-1g | 1 g | $3000 | in stock | |
2584-5g | 5 g | please inquire | in stock |
Disuccinimidyl glutarate (DSG)
Homobifunctional crosslinker with two NHS ester groups at each end of a short 5-atom (7.7 angstrom) spacer.
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Cat. # | Quantity | Price | Lead time | Buy this product |
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4018-100mg | 100 mg | $95 | in stock | |
4018-1g | 1 g | $410 | in stock |
Hexynoic acid NHS ester
Hexynoic acid NHS ester for the labeling of biomolecules with alkyne group for copper-catalyzed click chemistry.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
41720 | 25 mg | $95 | in stock | |
51720 | 50 mg | $180 | in stock | |
61720 | 100 mg | $290 | in stock | |
91720 | 1 g | please inquire | in stock |
Hexynoic acid STP ester
Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
569-25mg | 25 mg | $95 | in stock | |
569-100mg | 100 mg | $185 | in stock | |
569-500mg | 500 mg | $850 | in stock |
Hydroxy-PEG2-thiol
Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2389-100mg | 100 mg | $90 | in stock | |
2389-1g | 1 g | $270 | in stock |
Hydroxy-PEG3-thiol
PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2368-100mg | 100 mg | $110 | in stock |
Iodo-PEG3-carboxylic acid
A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2063-1g | 1 g | $190 | in stock | |
2063-5g | 5 g | $795 | in stock | |
2063-10g | 10 g | please inquire | in stock |
Iodo-PEG3-iodide
Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2098-1g | 1 g | $290 | in stock |
PEG3-dicarboxylic acid
PEG3-dicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
1715-1g | 1 g | $490 | in stock | |
1715-5g | 5 g | $890 | in stock | |
1715-10g | 10 g | $1370 | in stock |
PEG3-tetrazine
PEG3 tetrazine is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
1978-250mg | 250 mg | $390 | in stock | |
1978-1g | 1 g | $950 | in stock |
Pentynoic acid STP ester
An activated ester for the introduction of alkyne into peptides/proteins and click reaction.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
30720 | 10 mg | $110 | in stock | |
40720 | 25 mg | $210 | in stock | |
50720 | 50 mg | $410 | in stock | |
60720 | 100 mg | $595 | 10 days |
sulfo-Cyanine7 bis-NHS ester
sulfo-Cyanine7 bis-NHS ester is a bifunctional derivative of water-soluble near-infrared sulfo-Cyanine7. It contains two activated ester functional groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
153D0 | 1 mg | $125 | in stock | |
253D0 | 5 mg | $325 | in stock | |
453D0 | 25 mg | $850 | in stock | |
553D0 | 50 mg | $1490 | in stock | |
653D0 | 100 mg | $1990 | in stock |
Tetraglycine hydrochloride
Tetraglycine is an oligopeptide composed of four glycine monomers. It is used as a bifunctional linker with amino and carboxyl groups.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
3049-500mg | 500 mg | $319 | in stock |
Thalidomide-carboxylic acid
Thalidomide-containing building block with carboxylic acid functionality for convenient PROTAC molecule assembly by attachment amino-functionalized linkers and ligands to thalidomide via 4-O-position.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
4169-100mg | 100 mg | $160 | in stock | |
4169-500mg | 500 mg | $510 | in stock | |
4169-1g | 1 g | $740 | in stock |
Thalidomide-O-PEG2-azide
Thalidomide-containing building block with PEG2-linker and azide function group for conjugation with alkyne-functionalized linkers and target protein ligands through click chemistry reactions.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
4154-25mg | 25 mg | $189 | in stock | |
4154-100mg | 100 mg | $489 | in stock |
Thalidomide-O-PEG2-carboxylic acid
Thalidomide-containing building block with PEG2-linker and carboxylic group for conjugation with amino-functionalized linkers and target protein ligands.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
4192-25mg | 25 mg | $145 | in stock | |
4192-100mg | 100 mg | $425 | in stock |
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