Cycloalkenes in Reactive groups
Cycloalkenes are strained alkenes, tetrazine-reactive derivatives for inverse electron-demand Diels-Alder cycloaddition reaction (IEDDA).
Trans-cyclooctene (TCO) is one of the most used cycloalkenes for bioconjugation tasks. TCO-Tetrazine ligation possesses ultrafast kinetics, selectivity, high yielding, and long-term aqueous stability, which is important in low-concentration applications such as protein-protein conjugations, etc.
AF 488 TCO
AF 488-containing derivative of trans-cyclooctene (TCO) for conjugation with tetrazine via the inverse electron-demand Diels-Alder cycloaddition reaction (IEDDA).
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
118H0 | 1 mg | $199 | in stock | |
218H0 | 5 mg | $649 | in stock | |
418H0 | 25 mg | $1789 | in stock |
TCO phosphoramidite C6
Trans-cyclooctene (TCO) amidite is used to introduce a TCO moiety into substrates containing primary or secondary hydroxyl group
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
4017-100mg | 100 mg | $480 | in stock | |
4017-250mg | 250 mg | $920 | in stock | |
4017-1g | 1 g | please inquire | in stock |
TCO-PEG4-NHS ester (axial isomer)
A heterobifunctional linker with trans-cyclooctene and NHS ester groups flanking PEG4 (tetraethylene glycol) for labeling of antibodies, proteins, and other primary amine-containing biomolecules.
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Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
3056-10mg | 10 mg | $145 | in stock | |
3056-25mg | 25 mg | $225 | in stock | |
3056-100mg | 100 mg | $550 | in stock |
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