sulfo-Cyanine3 tetrazine
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
113E0 | 1 mg | $125 | in stock | |
213E0 | 5 mg | $325 | in stock | |
313E0 | 10 mg | $470 | in stock | |
413E0 | 25 mg | $850 | in stock | |
513E0 | 50 mg | $1490 | in stock | |
613E0 | 100 mg | $1990 | in stock |
Tetrazine-trans-cyclooctene ligation is among the fastest bioconjugation reactions known to date.
This water-soluble sulfo-Cyanine3 derivative contains methyltetrazine moiety for the coupling with trans-cyclooctenes. Methyltetrazines possess optimal stability at physiological pH, while maintaining extremely high reactivity towards cyclooctenes.
The fluorophore is bright, photostable, and is also very well visible with naked eye.
Absorption and emission spectra of Cyanine3
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This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).BDP® 630/650-X-NHS ester
BDP 630/650 is a borondipyrromethene fluorophore tuned to Cyanine5 excitation and emission channels. The dye is bright and highly photostable. It is useful for fluorescence polarization assays. This is an amine-reactive NHS ester derivative.General properties
Appearance: | red powder |
Molecular weight: | 838.05 |
Molecular formula: | C40H44KN7O7S2 |
IUPAC name: | Potassium (E)-2-[(E)-3-{3,3-Dimethyl-1-[6-({[p-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl}amino)-6-oxohexyl]-5-(oxysulfonyl)-3H-indol-2-yl}-2-propenylidene]-1-methyl-3,3-dimethyl-5-indolinesulfonate |
Solubility: | soluble in water (0.43 M = 36 g/L), DMF, DMSO |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 548 |
ε, L⋅mol−1⋅cm−1: | 162000 |
Emission maximum, nm: | 563 |
Fluorescence quantum yield: | 0.1 |
CF260: | 0.03 |
CF280: | 0.06 |
Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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