TO-TAP-1, green fluorescent nucleic acid stain

Nuclei Cell viability and apoptosis Microscopy Flow cytometry
Cat. # Quantity Price Lead time
A3610 50 uL, 5 mM/DMSO $85 in stock
23610 200 uL, 5 mM/DMSO $320 in stock
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TO-TAP-1 (Thiazole Orange Monomer, also known as TO-PRO®-1) is a green fluorescent carbocyanine monomeric dye. TO-TAP-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.

The bright fluorescence signal and low background make TO-TAP-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. TO-TAP-1 is non-cytotoxic and may be used for long-term monitoring of cell viability and dead cell detection in culture.

TO-TAP-1, green fluorescent nucleic acid stain, 23610
TO-TAP-1, green fluorescent nucleic acid stain, 23610
TO-TAP-1, green fluorescent nucleic acid stain, 23610
Structure of TO-TAP-1
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Absorption and emission spectra of TO-TAP-1 (DNA–dye complex)

Absorption and emission spectra of TO-TAP-1 (DNA–dye complex)

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General properties

Appearance: orange solution
Molecular weight: 645.39
CAS number: 157199-59-2
Molecular formula: C24H29I2N3S
IUPAC name: Quinolinium, 4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]-1-[3-(trimethylammonio)propyl]-, diiodide
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 513
Emission maximum, nm: 533
TO-PRO® is the trademark of Molecular Probes.
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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