Biotin-PEG4-alkyne

Biotinylation Alkynes Click chemistry
Cat. # Quantity Price Lead time
2615-50mg 50 mg $125 in stock
2615-100mg 100 mg $185 in stock
2615-1g 1 g $990 in stock
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Biotin-PEG4-alkyne is a click chemistry biotinylation tool. This reagent allows the labeling of azide-containing molecules with biotin via copper-catalyzed click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection.

This structure of biotin alkyne features a long hydrophilic PEG4 linker that separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker also enhances aqueous solubility to facilitate conjugation.

Biotin-PEG4-alkyne, 2615-100mg
Biotin-PEG4-alkyne, 2615-100mg
Biotin-PEG4-alkyne, 2615-100mg
Structure of Biotin-PEG4-alkyne
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General properties

Appearance: white powder
Molecular weight: 457.59
CAS number: 1262681-31-1
Molecular formula: C21H35N3O6S
Solubility: good in water, DMSO, DCM, DMF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Liang, J.; Han, J.; Gao, X.; Jia, H.; Li, R.; Tse, E. C. M.; Li, Y. Clickable APEX2 Probes for Enhanced RNA Proximity Labeling in Live Cells. Anal. Chem., 2024, 96(2), 685–693. doi: 10.1021/acs.analchem.3c03614
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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