BTTAA ligand

Click chemistry

Cat. #	Quantity	Price	Lead time
3253-100mg	100 mg	$159	in stock
3253-500mg	500 mg	$560	in stock
3253-1g	1 g	$990	in stock
3253-5g	5 g	please inquire	in stock

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BTTAA is the newest generation of water-soluble ligands for Cu(I)-catalyzed azide-alkyne click chemistry reactions (CuAAC). It maintains the Cu(I) oxidation state in the catalyst and protects biomolecules from oxidative damage during the labeling.

BTTAA provides much more significant rate enhancement than previous generation ligands (e.g., THPTA or TBTA) and suppresses cell cytotoxicity by further lowering copper loading in the catalyst formulation.

A stock solution can be prepared in ddH₂O and stored at −20°C. Avoid freeze-thaw cycles.

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General properties

Appearance:	off-white to grey solid
Molecular weight:	430.52
CAS number:	1334179-85-9
Molecular formula:	C₁₉H₃₀N₁₀O₂
IUPAC name:	2-(4-((bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid
Solubility:	Soluble in water, DMSO, DMF, MeOH
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications