HPG (L-Homopropargylglycine)

Cat. # Quantity Price Lead time
3313-25mg 25 mg $99 in stock
3313-100mg 100 mg $229 in stock
3313-1g 1 g please inquire in stock
Found better price? Let us know and we will propose the way forward!

L-Homopropargylglycine (HPG) is a noncanonical amino acid analog of methionine that contains a terminal alkyne moiety. HPG-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.

HPG is the cell-permeable compound randomly incorporated into synthesizing protein instead of methionine during translation. The resulting alkyne-labeled full-length proteins can be detected via copper-catalyzed click reaction with fluorescent or biotin-labeled azides and used for subsequent microscopic imaging or purification tasks.

Customers also purchased with this product

dsGreen Nucleic Acid Gel Staining Solution, 10,000×

dsGreen for staining dsDNA in agarose and polyacrylamide gels.

6-Carboxy-H2DCFDA (6-carboxy-2',7'-dichlorodihydrofluorescein)

A reagent for detecting reactive oxygen species (ROS) in living cells. This carboxylated H2DCFDA analog has two additional negative charges that impede its leakage out of the cell.

AF 647 azide

Bright and photostable azide AF 647 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.

General properties

Appearance: off-white solid
Molecular weight: 163.60
CAS number: 942518-19-6
Molecular formula: C6H10ClNO2
Solubility: good in water, DMSO
Quality control: NMR 1H and GCMS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Baleva, M.V.; Piunova, U.; Chicherin, I.; Vasilev, R.; Levitskii, S.; Kamenski, P. Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells. International Journal of Molecular Sciences, 2024, 25(1), 93. doi: 10.3390/ijms25010093
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.