sulfo-Cyanine7 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 15320 | 1 mg | $125 | in stock | |
| 25320 | 5 mg | $325 | in stock | |
| 45320 | 25 mg |
$850
|
in stock | |
| 55320 | 50 mg |
$1490
|
in stock | |
| 65320 | 100 mg |
$1990
|
in stock |
Water-soluble near-infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.
sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.
Near-infrared fluorescent imaging takes advantage of the transparency of biological tissues at a particular range of wavelengths. The method is non-destructive and allows to monitor of the distribution of various labeled molecules in live organisms.
sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye-labeled molecules can be subsequently used for various research and drug design-related experiments.
This reagent has high water solubility and is especially useful for labeling delicate proteins and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in the organic phase is also available.
sulfo-Cyanine7 absorbance and emission spectra
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EdU is a nucleoside that is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by click chemistry reaction with fluorescent dye azides to reveal cell proliferation.Cyanine3 DBCO
Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper-free click chemistry.General properties
| Appearance: | dark green powder |
| Molecular weight: | 844.05 |
| CAS number: | 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt); 477908-53-5 (N-Ethyl) |
| Molecular formula: | C41H46N3KO10S2 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 240600 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.24 |
| CF260: | 0.04 |
| CF280: | 0.04 |
Product citations
- Stinson, B.M.; Carney, S.M.; Walter, J.C.; Loparo, J.J. Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining. Nature Communications, 2024, 15, 1250. doi: 10.1038/s41467-024-45553-z
- Niu, L.; Jang, E.; Chin, A.L.; Huo, Z.; Wang, W.; Cai, W.; Tong, R. Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity. Science Advances, 2024, 10(16), eadk7695. doi: 10.1126/sciadv.adk7695
- Zeng, Z.; Tan, R.; Chen, S.; Chen, H.; Liu, Z.; Liu, L.; Li, M.; Chen, Y. Di-PEGylated insulin: A long-acting insulin conjugate with superior safety in reducing hypoglycemic events. Acta Pharmaceutica Sinica B, 2024, 14(6), 2761-2772. doi: 10.1016/j.apsb.2024.02.022
- Feng, X.A.; Ness, K.M.; Liu, C.; Ahmed, I.; Bowman, G.D.; Ha, T.; Wu, C. GAGA Factor Overcomes 1D Diffusion Barrier by 3D Diffusion in Search of Nucleosomal Targets. bioRxiv, 2023, preprint. doi: 10.1101/2023.07.14.549009
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