TAMRA azide, 5-isomer
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A7130 | 1 mg | $110 | in stock | |
| B7130 | 5 mg | $135 | in stock | |
| C7130 | 10 mg | $210 | in stock | |
| D7130 | 25 mg | $390 | in stock | |
| E7130 | 50 mg |
$595
|
in stock | |
| F7130 | 100 mg |
$790
|
in stock |
TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for click chemistry. Pure 5-isomer. TAMRA is often used as a FRET acceptor for FAM fluorophore. Can replace DyLight 549.
Absorption and emission spectra of 5-TAMRA
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General properties
| Appearance: | violet solid / solution |
| Mass spec M+ increment: | 512.2 |
| Molecular weight: | 512.56 |
| CAS number: | 825651-66-9 |
| Molecular formula: | C28H28N6O4 |
| Solubility: | good in polar organic solvents (DMF, DMSO, alcohols), low in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 541 |
| ε, L⋅mol−1⋅cm−1: | 84000 |
| Emission maximum, nm: | 567 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.32 |
| CF280: | 0.19 |
Product citations
- Yu, T.; Hou, D.; Zhao, J.; Lu, X.; Greentree, W.K.; Zhao, Q.; Yang, M.; Conde, D.-G.; Linder, M.E.; Lin, H. NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation. Cell reports, 2024, 43(4), 114070. doi: 10.1016/j.celrep.2024.114070
- Liu, Y.; Hou, D.; Chen, W.; Lu, X.; Komaniecki, G.P.; Xu, Y.; Yu, T.; Zhang, S.M.; Linder, M.E.; Lin, H. MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(34), e2403392121. doi: 10.1073/pnas.2403392121
- Komaniecki, G.; Camarena, M. D. C.; Gelsleichter, E.; Mendoza, R.; Subler, M.; Windle, J. J.; Dozmorov, M. G.; Lai, Z.; Sarkar, D.; Lin, H. Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry, 2023, 62(2), 543–553. doi: 10.1021/acs.biochem.2c00583
- Reddi, R. N.; Rogel, A.; Gabizon, R.; Rawale, D. G.; Harish, B.; Marom, S.; Tivon, B.; Arbel, Y. S.; Gurwicz, N.; Oren, R.; David, K.; Liu, J.; Duberstein, S.; Itkin, M.; Malitsky, S.; Barr, H.; Katz, B.-Z.; Herishanu, Y.; Shachar, I.; Shulman, Z.; London, N. Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry. J. Am. Chem. Soc, 2023, 145(6), 3346–3360. doi: 10.1021/jacs.2c08853
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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