TCO-PEG4-NHS ester (axial isomer)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 3056-10mg | 10 mg | $145 | in stock | |
| 3056-25mg | 25 mg | $225 | in stock | |
| 3056-100mg | 100 mg |
$550
|
in stock |
TCO-PEG4-NHS ester is a bifunctional linker with trans-cyclooctene (TCO) and NHS ester groups flanking PEG4 (tetraethylene glycol).
The PEG spacer increases solubility in aqueous media and provides a long and flexible connection that minimizes steric hindrance involved with ligation.
The amine-reactive N-hydroxysuccinimide residue provides easy attachment to almost any primary or secondary amine group, such as protein, peptide, or small molecule amine.
Trans-cyclooctene readily reacts with tetrazines via inverse electron-demand Diels-Alder cycloaddition (IEDDA). TCO-Tetrazine ligation possesses ultrafast kinetics, selectivity, and long-term aqueous stability, which is important in low-concentration applications such as protein-protein conjugations, etc.
Recommended protocol
Calculator
Customers also purchased with this product
DBCO-PEG6-NHS ester
A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).R6G azide, 5-isomer
Rhodamine 6G is a xanthene dye that has been used for DNA sequencing and qPCR. This azide derivative is used for the attachment of the dye to DNA and other molecules by means of click chemistry.Alkyne-PEG4-phosphoramidite
Alkyne phosphoramidite for conjugation of oligonucleotides with biomolecules.General properties
| Appearance: | colorless syrup |
| Molecular weight: | 514.57 |
| CAS number: | 1621096-79-4 |
| Molecular formula: | C24H38N2O10 |
| Solubility: | DMSO, DMF, THF, Acetonitrile, Dichloromethane |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Your cart is empty
$ 
