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Metabolic labeling
Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)

Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)

Azides Copper-free click chemistry Click chemistry Glycan labeling

Cat. #	Quantity	Price	Lead time
3706-5mg	5 mg	$129	in stock
3706-25mg	25 mg	$240	in stock
3706-100mg	100 mg	$630	in stock

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The tetraacetylated N-Azidoacetyl-galactosamine (Ac4GalNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GalNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylgalactosamine (GalNAc).

The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.

The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.

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DBCO-amine trifluoroacetate

Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.

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General properties

Appearance:	white crystals
Molecular weight:	430.37
CAS number:	653600-56-7
Molecular formula:	C₁₆H₂₂N₄O₁₀
Solubility:	DMSO, DMF, DCM, THF, Chloroform
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.