VdU (5-Vinyl-2'-deoxyuridine)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| B2540 | 5 mg | – | in stock | |
| D2540 | 25 mg | $225 | in stock | |
| F2540 | 100 mg |
$785
|
in stock |
VdU (5-Vinyl-2’-deoxyuridine) is a synthetic analog of thymidine that can be used to study de novo DNA synthesis and cell proliferation. It is a potential replacement for BrdU (5-Bromo-2’-deoxyuridine) or EdU (5-Ethynyl-2’-deoxyuridine).
VdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. The resulting vinyl-functionalized DNA can be detected by introducing either a biotin or fluorescent dye group via a cooper-free alkene-tetrazine reaction (also known as Inverse electron demand Diels-Alder ligation or IEDDA) and used for subsequent DNA purification or cell imaging tasks.
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Azide derivative of Cyanine3 fluorescent dye for сlick сhemistry.AmdU (5-Azidomethyl-2'-deoxyuridine)
Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.General properties
| Appearance: | yellowish solid |
| Molecular weight: | 254.24 |
| CAS number: | 55520-67-7 |
| Molecular formula: | C11H14N2O5 |
| Solubility: | in DMSO |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
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