EdU (5-Ethynyl-2'-deoxyuridine)
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
A0540 | 5 mg | – | in stock | |
10540 | 100 mg | $120 | in stock | |
20540 | 250 mg | $195 | in stock | |
30540 | 500 mg | $345 | in stock | |
40540 | 1 g | $590 | in stock | |
60540 | 5 g | please inquire | in stock |
EdU (5-ethynyl-2’-deoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. After EdU incorporation, DNA containing ethynyl groups can be ligated by click chemistry reaction with various dye azides. Fluorescent DNA can be detected with microscopy, or cells can be sorted with FACS.
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Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.Thiazole Orange
Cyanine dye that is essentially dark in solution but has a bright fluorescence in double-stranded DNA and RNA complexes.General properties
Appearance: | light beige to light brown solid |
Molecular weight: | 252.22 |
CAS number: | 61135-33-9 |
Molecular formula: | C11H12N2O5 |
Solubility: | in water, DMSO |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
MSDS: | Download |
Product specifications |
Product citations
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- Goedhart, J. Studentsourcing—Aggregating and reusing data from a practical cell biology course. PLOS Computational Biology, 2024, 20(2), e1011836. doi: 10.1371/journal.pcbi.1011836
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- Alruwaili, M.M.; Zonneville, J.; Naranjo, M.N.; Serio, H.; Melendy, T.; Straubinger, R.M.; Gillard, B.; Foster, B.A.; Rajan, P.; Attwood, K.; Chatley, S.; Iyer, R.; Fountzilas, C.; Bakin, A.V. A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers. Cell Reports Medicine, 2024, 5(3), 101434. doi: 10.1016/j.xcrm.2024.101434
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