Azide-PEG2-carboxylic acid

Cat. # Quantity Price Lead time
2816-250mg 250 mg $230 $199 in stock
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Azide-PEG2-carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups.

This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.

The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (сlick сhemistry reactions), and the carboxyl group can be activated and react with various amines.

The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.

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General properties

Appearance: yellow liquid
Molecular weight: 203.20
CAS number: 1312309-63-9
Molecular formula: C7H13N3O4
IUPAC name: 3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
Solubility: good in water and most organic solvents
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
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