Cyanine7 alkyne
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A50B0 | 1 mg | $125 | in stock | |
| B50B0 | 5 mg | $260 | in stock | |
| C50B0 | 10 mg | $325 | in stock | |
| D50B0 | 25 mg |
$510
|
in stock | |
| E50B0 | 50 mg |
$895
|
in stock | |
| F50B0 | 100 mg |
$1490
|
in stock |
Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7®. The alkyne can be conjugated to a variety of azides via copper-catalyzed click chemistry.
The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.
Absorbance and emission spectra of Cyanine7
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Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.General properties
| Appearance: | green powder |
| Mass spec M+ increment: | 586.4 |
| Molecular weight: | 622.28 |
| CAS number: | 1998119-13-3 (chloride), 1954687-62-7 |
| Molecular formula: | C40H48ClN3O |
| Solubility: | good in DMSO, DMF, alcohols |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 199000 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.3 |
| CF260: | 0.022 |
| CF280: | 0.029 |
Product citations
- Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
- Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
- Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
- Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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