Cyanine7.5 maleimide
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
16080 | 1 mg | $125 | in stock | |
26080 | 5 mg | $260 | in stock | |
46080 | 25 mg | $510 | in stock | |
56080 | 50 mg | $895 | in stock | |
66080 | 100 mg | $1490 | in stock |
Thiol-reactive, near-infrared dye Cyanine7.5 for labeling of protein SH groups, an analog of Cy7.5® maleimide.
Most proteins contain sulfhydryl groups which can be selectively labeled with maleimides. With this reagent, these proteins can be converted to near-infrared (NIR) fluorescent conjugates. After it, the conjugates can be used in non-invasive live organism imaging to study distribution of the protein in tissues and organs.
Cyanine7.5 absorbance and emission spectra
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Cyanine7.5 carboxylic acid
Cyanine7.5 - unactivated NIR cyanine dye carboxylic acid.
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AmdU (5-Azidomethyl-2'-deoxyuridine)
Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.Cyanine7 DBCO
NIR fluorescent dye functionalized with cyclooctyne moiety for copper free click chemistry conjugation with azides.General properties
Appearance: | green powder |
Molecular weight: | 807.46 |
Molecular formula: | C51H55ClN4O3 |
Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 788 |
ε, L⋅mol−1⋅cm−1: | 223000 |
Emission maximum, nm: | 808 |
Fluorescence quantum yield: | 0.10 |
Product citations
- Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
Cy® is a trademark of GE Healthcare.
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