DBCO-amine trifluoroacetate

Cat. # Quantity Price Lead time
1280-100mg 100 mg $218 in stock
1280-500mg 500 mg $678 in stock
1280-1g 1 g $1200 $1018 in stock
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Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.

Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain-promoted alkyne azide cycloaddition (SPAAC) – a copper-free click chemistry reaction. DBCO reacts instantly with azides. The reaction rate is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines.

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General properties

Appearance: beige to brawn solid
Molecular weight: 432.44
Molecular formula: C23H23F3N2O3
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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