Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
3159-5mg | 5 mg | $129 | in stock | |
3159-25mg | 25 mg | $240 | in stock | |
3159-100mg | 100 mg | $630 | in stock |
The tetraacetylated N-Azidoacetyl-mannosamine (Ac4ManNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.
Ac4ManNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylmannosamine (ManNAc).
The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.
The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.
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Appearance: | white solid |
Molecular weight: | 430.37 |
CAS number: | 361154-30-5 |
Molecular formula: | C16H22N4O10 |
Solubility: | Soluble to 100 mM in DMSO |
Quality control: | NMR 1H and HPLC-MS (95+%) |
Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |