sulfo-Cyanine5 tetrazine

Tetrazines Copper-free click chemistry sulfo-Cyanine5

Cat. #	Quantity	Price	Lead time
133E0	1 mg	$125	in stock
233E0	5 mg	$325	in stock
333E0	10 mg	$470	in stock
433E0	25 mg	$850	in stock
533E0	50 mg	$1490	in stock
633E0	100 mg	$1990	in stock

Found better price? Let us know and we will propose the way forward!

TCO (tetrazine – trans-cyclooctene) ligation is one of the fastest reactions used for bioconjugation. It is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefins.

sulfo-Cyanine5 tetrazine is a fluorophore derivative bearing a tetrazine group for the TCO-ligation-based labeling.

This reagent possesses good aqueous solubility and stability in biological environments.

Download in
ChemDraw format

Absorption and emission spectra of Sulfo-Cyanine5

Customers also purchased with this product

BDP® FL DBCO

BDP FL DBCO is a dye cyclooctyne for copper-free click chemistry reactions with azides. Its absorption and emission wavelengths correspond to those of fluorescein (FAM), but BDP FL is significantly more photostable.

Cyanine7.5 alkyne

Reactive near infrared (NIR) dye for click chemistry containing a terminal alkyne group.

Add this product to your cart and
get free express delivery

General properties

Appearance:	dark blue solid
Molecular weight:	864.09
Molecular formula:	C₄₂H₄₆KN₇O₇S₂
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	646
ε, L⋅mol⁻¹⋅cm⁻¹:	271000
Emission maximum, nm:	662
Fluorescence quantum yield:	0.28
CF₂₆₀:	0.04
CF₂₈₀:	0.04

Product citations

Comeo, E.; Goulding, J.; Lin, C.-Y.; Groenen, M.; Woolard, J.; Kindon, N. D.; Harwood, C. R.; Platt, S.; Briddon, S. J.; Kilpatrick, L. E.; Scammells, P. J.; Hill, S. J.; Kellam, B. Ligand-Directed Labeling of the Adenosine A1 Receptor in Living Cells. J. Med. Chem., 2024, 67(14), 12099–12117. doi: 10.1021/acs.jmedchem.4c00835
Kerr, M. D.; McBride, D. A.; Johnson, W. T.; Chumber, A. K.; Najibi, A. J.; Seo, B. R.; Stafford, A. G.; Scadden, D. T.; Mooney, D. J.; Shah, N. J. Immune-Responsive Biodegradable Scaffolds for Enhancing Neutrophil Regeneration. Bioengineering & Translational Medicine, 2023, 8(1), e10309. doi: 10.1002/btm2.10309
Kerr, M.D.; Johnson, W.T.; McBride, D.A.; Chumber, A.K.; Shah, N.J. Biodegradable scaffolds for enhancing vaccine delivery. Bioengineering & translational medicine, 2023, 8(6), e10591. doi: 10.1002/btm2.10591