FAM maleimide, 6-isomer
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
24180 | 5 mg | – | in stock | |
44180 | 25 mg | $260 | in stock | |
54180 | 50 mg | $370 | in stock | |
64180 | 100 mg | $525 | in stock |
FAM (fluorescein) is a bright fluorophore which is compatible with various fluorescence detection instruments. FAM is a universal dye that is useful for microscopy, qPCR and many other methods as well as for FRET-based and fluorescence polarization based binding assays.
FAM maleimide is a thiol reactive dye for the labeling of proteins, peptides, and other thiolated molecules.
FAM absorbance and emission spectra
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sulfo-Cyanine3.5 NHS ester
Amine-reactive activated ester of water-soluble, sulfonated sulfo-Cyanine3.5 dye.FAM tetrazine, 6-isomer
This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).AF 430 NHS ester
AF 430 is a hydrophilic coumarin dye with emission in the green-yellow range. The NHS ester is used for the labeling of amine groups.General properties
Appearance: | yellow solid |
Mass spec M+ increment: | 498.4 |
Molecular weight: | 498.44 |
Molecular formula: | C27H18N2O8 |
Solubility: | good in DMSO, DMF |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 492 |
ε, L⋅mol−1⋅cm−1: | 74000 |
Emission maximum, nm: | 517 |
Fluorescence quantum yield: | 0.93 |
CF260: | 0.22 |
CF280: | 0.17 |
Product citations
- Huang, S.; Gao, Y.; Ma, L.; Jia, B.; Zhao, W.; Yao, Y.; Li, W.; Lin, T.; Wang, R.; Song, J.; Zhang, W. Design of pH-responsive antimicrobial peptide melittin analog-camptothecin conjugates for tumor therapy. Asian Journal of Pharmaceutical Sciences, 2024, 19(1), 100890. doi: 10.1016/j.ajps.2024.100890
- Gabashvili, A.N.; Alexandrushkina, N.A.; Mochalova, E.N.; Goliusova, D.V.; Sapozhnikova, E.N.; Makarevich, P.I.; Nikitin, P.I. Internalization of transferrin-tagged Myxococcus xanthus encapsulins into mesenchymal stem cells. Experimental Biology and Medicine, 2024, 249(3), 10055. doi: 10.3389/ebm.2024.10055
- Peterson, B. G.; Hwang, J.; Russ, J. E.; Schroeder, J. W.; Freddolino, P. L.; Baldridge, R. D. Deep Mutational Scanning Highlights a Role for Cytosolic Regions in Hrd1 Function. Cell Reports, 2023, 42(11), 113451. doi: 10.1016/j.celrep.2023.113451
- Kalinovsky, D. V.; Kholodenko, I. V.; Kibardin, A. V.; Doronin, I. I.; Svirshchevskaya, E. V.; Ryazantsev, D. Y.; Konovalova, M. V.; Rozov, F. N.; Larin, S. S.; Deyev, S. M.; Kholodenko, R. V. Minibody-Based and ScFv-Based Antibody Fragment-Drug Conjugates Selectively Eliminate GD2-Positive Tumor Cells. International Journal of Molecular Sciences, 2023, 24(2), 1239. doi: 10.3390/ijms24021239
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