DBCO-STP ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2584-5mg | 5 mg | – | in stock | |
2584-10mg | 10 mg | $90 | in stock | |
2584-25mg | 25 mg | $180 | in stock | |
2584-100mg | 100 mg |
$450
|
in stock | |
2584-500mg | 500 mg |
$1700
|
in stock | |
2584-1g | 1 g |
$3000
|
in stock | |
2584-5g | 5 g | please inquire | in stock |
Dibenzocyclooctyne sulfotetrafluorophenyl ester (DBCO-STP ester) is a water-soluble reagent that can be used for the modification of peptides, antibodies, proteins, and other molecules containing the -NH2 group.
STP esters are hydrolyzed much more slowly than NHS esters, thus allowing efficient biomolecule modification in the aqueous medium.
The dibenzocyclooctyne (DBCO) moiety, which is also known as ADIBO or DIBAC, is the most common substrate for copper-free click chemistry reactions that are promoted by ring strain. In this reaction in the absence of a Cu(I) catalyst, DBCO derivatives react with biomolecules functionalized by the azide group to result in stable triazoles.
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Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.General properties
Appearance: | beige powder |
Molecular weight: | 569.46 |
Molecular formula: | C26H16NF4O6SNa |
Solubility: | good in water, DCM, DMF, DMSO |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |
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