ATFB SE (N-Succinimidyl 4-Azidotetrafluorobenzoate)

Cat. # Quantity Price Lead time
2574-250mg 250 mg $146 in stock
2574-1g 1 g $420 in stock
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N-Succinimidyl 4-Azido-2,3,5,6—tetrafluorobenzoate (ATFB SE, ATFB-OSu) is a photo-activatable linker used as a versatile labeling agent for investigating biological receptors and for direct coating the surfaces of carbon and organic-based polymers. Upon exposure to light (max. absorption at 258nm), ATFB produces stabilized nitrene intermediates that readily undergo insertion and addition reactions with nearby molecules in moderate to good yields.

This compound is an activated N-hydroxysuccinimide ester (NHS ester, SE) derivative that can react to almost any primary or secondary amine group of biomolecules, such as proteins and peptides, as well as to small-molecule amines.

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General properties

Appearance: white solid or crystalline powder
Molecular weight: 332.17
CAS number: 126695-58-7
Molecular formula: C11H4F4N4O4
IUPAC name: (2,5-dioxopyrrolidin-1-yl) 4-azido-2,3,5,6-tetrafluorobenzoate
Solubility: DMSO DMF, ethyl acetate, chlorinated organics
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
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