RH 237, potentiometric probe

Neuroscience Microscopy Membrane potential measurement

Cat. #	Quantity	Price	Lead time	Buy this product
3734-5mg	5 mg	$139	in stock

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RH 237, also called N-(4-sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, is a fast-response potential-sensitive probe. RH 237 is primarily used for imaging membrane potential, synaptic activity, and ion channel activity of neurons. However, the dye is also suitable for imaging the functional activity of mitochondria and heart cells.

Excitation/emission maxima of RH 237 in ethanol are 532/777 nm, respectively. In cell membranes, the spectra of the dye are typically blue-shifted by approximately 20 nm for excitation and 80 nm for emission peaks.

Use 1-5 μM working concentration as a starting point. The exact dye concentration should be defined experimentally.

Structure of RH 237, potentiometric probe

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Absorption and emission spectra of RH 237

General properties

Appearance:	dark violet powder
Molecular weight:	496.72
CAS number:	83668-91-1
Molecular formula:	C₂₉H₄₀N₂O₃S
IUPAC name:	N-(4-Sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, inner salt
Solubility:	water, methanol, DMSO
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	532
Emission maximum, nm:	777

Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.