AF 568 DBCO
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
1158F0 | 1 mg | $140 | in stock | |
2158F0 | 5 mg | $450 | in stock | |
4158F0 | 25 mg | $1460 | in stock | |
5158F0 | 50 mg | $1890 | in stock | |
6158F0 | 100 mg | $2990 | in stock |
Dibenzocyclooctyne (DBCO, DBCO, ADIBO) is one of the most reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition). The rate of interaction of DBCO with azides is significantly higher than that of other cyclooctynes, as well as Cu-catalyzed click reaction (CuAAC). Unlike other cyclooctynes, DBCO does not interact with tetrazines, which makes it possible to use it in bioorthogonal reactions together with trans-cyclooctenes and tetrazines.
AF 568 is a bright, photostable, and hydrophilic fluorophore that emits in the orange channel. The absorption maximum is 572 nm. The emission maximum is 598 nm.
AF 568 DBCO allows fluorescent labeling of azide-containing biomolecules inside living cells and whole organisms without the negative effect of copper ions on them, and inanimate samples.
Absorption and emission spectra of AF 568
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Dibenzocyclooctyne (DBCO, ADIBO) containing the green fluorophore AF 488 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples. Pure 5-isomer.General properties
Appearance: | dark violet solid |
Molecular weight: | 1197.53 |
Molecular formula: | C66H80N6O11S2 |
Quality control: | NMR 1H and HPLC-MS (95+%) |
Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 572 |
ε, L⋅mol−1⋅cm−1: | 94238 |
Emission maximum, nm: | 598 |
Fluorescence quantum yield: | 0.912 |