AMCA carboxylic acid

Cat. # Quantity Price Lead time
3357-25mg 25 mg $45 in stock
3357-100mg 100 mg $95 in stock
3357-1g 1 g $490 in stock
Found better price? Let us know and we will propose the way forward!

AMCA (aminomethylcoumarin acetate) is one of the brightest blue fluorescent dyes. This fluorophore has a relatively large Stoke’s shift, high resistance to photobleaching, and pH-independent fluorescence from pH 4 to 10. AMCA is a widely used fluorophore for multiple-color labeling due to its minimal fluorescence overlap with green- and longer wavelength-emitting fluorescent dyes.

AMCA carboxylic acid is a non-reactive form of AMCA dye that can be used as a reference standard in experiments involving AMCA dye conjugates. Besides, the carboxylic group can react with hydrazines, hydroxylamines, and amines using carbodiimides such as EDAC.

Absorption and emission spectra of AMCA

Absorption and emission spectra of AMCA

Customers also purchased with this product

AF 343 (Coumarin) X azide

AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.

AF 430 carboxylic acid

Non-reactive form of AF 430 fluorescent dye to be used as a reference standard.

AF 568 carboxylic acid

Non-reactive form of AF 568 fluorescent dye with a free carboxyl group.

General properties

Appearance: off-white solid
Molecular weight: 233.22
Molecular formula: C12H11NO4
Solubility: good in DMSO, DMF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 348
ε, L⋅mol−1⋅cm−1: 17400
Emission maximum, nm: 435
Fluorescence quantum yield: 0.91
CF260: 0.16
CF280: 0.13
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.