Cyanine5.5 NHS ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
17020 | 1 mg | $125 | in stock | |
27020 | 5 mg | $260 | in stock | |
47020 | 25 mg | $510 | in stock | |
57020 | 50 mg | $895 | in stock | |
67020 | 100 mg | $1490 | in stock |
Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester.
Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments.
This reagent can replace NHS esters of Cy5.5® and DyLight 680.
Cy5.5 absorbance and emission spectra
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JOE phosphoramidite is a xanthene dye phosphoramidite used in oligo synthesis. Its absorption and emission spectra are located between the FAM and TAMRA channels.BDP® 630/650 carboxylic acid
BDP 630/650 is a bright fluorophore for far red part of the spectrum. This dye is perfect for microscopy and fluorescence polarization assays. This is a carboxylic acid that can be activated for the coupling, or used as a control.
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6-Carboxy-H2DCFDA (6-carboxy-2',7'-dichlorodihydrofluorescein)
A reagent for detecting reactive oxygen species (ROS) in living cells. This carboxylated H2DCFDA analog has two additional negative charges that impede its leakage out of the cell.General properties
Appearance: | dark blue to violet solid |
Molecular weight: | 767.66 |
CAS number: | 2375105-86-3 |
Molecular formula: | C44H46N3BF4O4 |
IUPAC name: | 1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 684 |
ε, L⋅mol−1⋅cm−1: | 198000 |
Emission maximum, nm: | 710 |
Fluorescence quantum yield: | 0.2 |
CF260: | 0.07 |
CF280: | 0.03 |
Product citations
- Yun, W.S.; Yang, W.; Shim, M.K.; Song, S.; Choi, J.; Kim, J.; Kim, J.; Moon, Y.; Jo, S.H.; Lim, D.-K.; Kim, K. Accurately controlled tumor temperature with silica-coated gold nanorods for optimal immune checkpoint blockade therapy. Biomaterials Research, 2024, 28, 0024. doi: 10.34133/bmr.0024
- Broering, M.F.; Oseliero Filho, P.L.; Borges, P.P.; da Silva, L.C.C.; Knirsch, M.C.; Xavier, L.F.; Scharf, P.; Sandri, S.; Stephano, M.A.; de Oliveira, F.A.; Sayed, I.M.; Gamarra, L.F.; Das, S.; Fantini, M.C.A.; Farsky, S.H.P. Development of Ac2-26 Mesoporous Microparticle System as a Potential Therapeutic Agent for Inflammatory Bowel Diseases. International Journal of Nanomedicine, 2024, 19, 3537-3554. doi: 10.2147/IJN.S451589
- Han, G.; Kim, H.; Jang, H.; Kim, E.S.; Kim, S.H.; Yang, Y. Oral TNF-α siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease. Bioactive Materials, 2024, 34, 138-149. doi: 10.1016/j.bioactmat.2023.12.010
- Miao, L.; Yu, C.; Guan, G.; Luan, X.; Jin, X.; Pan, M.; Yang, Y.; Yan, J.; Chen, P.; Di, G. Extracellular Vesicles Containing GAS6 Protect the Liver from Ischemia-Reperfusion Injury by Enhancing Macrophage Efferocytosis via MerTK-ERK-COX2 Signaling. Cell Death Discov., 2024, 10(1), 1–13. doi: 10.1038/s41420-024-02169-y
Cy® is a trademark of Cytiva.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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