TAMRA NHS ester, 5-isomer

TAMRA (TMR, Tetramethylrhodamine) NHS esters Protein labeling
Cat. # Quantity Price Lead time
17120 1 mg –   in stock
27120 5 mg $210 in stock
47120 25 mg $350 in stock
57120 50 mg $595 in stock
67120 100 mg $790 in stock
Sample request
Found better price? Let us know and we will propose the way forward!

TAMRA (tetramethylrhodamine) is a xanthene dye of rhodamine series. This fluorophore has been used for quite a long time for the preparation of dual-labeled qPCR TaqMan oligonucleotide probes containing TAMRA and fluorescein (FAM).

Like many other xanthene fluorophores, TAMRA is available as two isomers (5- and 6-isomer) with nearly identical optical properties. This product is an isomerically pure 5-TAMRA.

TAMRA NHS is an amine-reactive reagent. It can be used to label proteins, peptides, and modified oligonucleotides containing amine groups.

TAMRA NHS ester, 5-isomer, 67120
TAMRA NHS ester, 5-isomer, 67120
TAMRA NHS ester, 5-isomer, 67120
Structure of 5-TAMRA NHS ester
Download in
ChemDraw format

Absorption and emission spectra of 5-TAMRA

Absorption and emission spectra of 5-TAMRA

Customers also purchased with this product

BDP® FL ceramide

Fluorescent derivative of sphingosine with emission in the green spectrum region for visualization of the Golgi apparatus in cells.

BDP® 630/650 amine

BDP 630/650 is a far red emitting fluorophore for Cyanine5 channel. This fluorophore is based on BDP (borondipyrromethene) core, which provides high quantum yield and photostability. This is an amine derivative of this dye.
Add this product to your cart and
get free express delivery

FAM hydrazide, 6-isomer

6-FAM hydrazide is a carbonyl reactive fluorescein (FAM) derivative. This product contains a pure 6-isomer of fluorescein.

General properties

Appearance: dark colored solid
Molecular weight: 527.53
CAS number: 321862-17-3
Molecular formula: C29H25N3O7
IUPAC name: (2,5-dioxopyrrolidin-1-yl) 3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylate
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

Product citations

  1. Sokolov, A. V.; Isakova-Sivak, I. N.; Mezhenskaya, D. A.; Kostevich, V. A.; Gorbunov, N. P.; Elizarova, A. Yu.; Matyushenko, V. A.; Berson, Yu. M.; Grudinina, N. A.; Kolmakov, N. N.; Zabrodskaya, Y. A.; Komlev, A. S.; Semak, I. V.; Budevich, A. I.; Rudenko, L. G.; Vasilyev, V. B. Molecular Mimicry of the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein: From the Interaction of Spike-Specific Antibodies with Transferrin and Lactoferrin to the Antiviral Effects of Human Recombinant Lactoferrin. Biometals, 2023, 36(3), 437–462. doi: 10.1007/s10534-022-00458-6
  2. Chen, H.; Zhang, Y.; Ma, X.; Zhou, B.; Liu, Z. Chemically-Modified Sepharose 6B Beads for Collection of Circulating Tumor Cells. Biomolecules, 2023, 13(7), 1071. doi: 10.3390/biom13071071
  3. Bresinsky, M.; Shahraki, A.; Kolb, P.; Pockes, S.; Schihada, H. Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. Journal of medicinal chemistry, 2023, 66(21), 15025-15041. doi: 10.1021/acs.jmedchem.3c01707
  4. Alexandrova, V. V.; Anisimov, M. N.; Zaitsev, A. V.; Mustyatsa, V. V.; Popov, V. V.; Ataullakhanov, F. I.; Gudimchuk, N. B. Theory of Tip Structure–Dependent Microtubule Catastrophes and Damage-Induced Microtubule Rescues. Proceedings of the National Academy of Sciences, 2022, 119(46), e2208294119. doi: 10.1073/pnas.2208294119
Show more (3)
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.