Cyanine7 DBCO
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A50F0 | 1 mg | $125 | in stock | |
| B50F0 | 5 mg | $260 | in stock | |
| C50F0 | 10 mg | $325 | in stock | |
| D50F0 | 25 mg |
$510
|
in stock | |
| E50F0 | 50 mg |
$895
|
in stock | |
| F50F0 | 100 mg |
$1490
|
in stock |
Cyanine7 DBCO is a NIR fluorescent dye with cycloalkyne moiety for the conjugation with azides by means of copper-free, strain-promoted alkyne-azide cycloaddition (SPAAC).
Azodibenzocyclooctyne (DBCO or ADIBO) fragment is a stable but active cycloalkyne that reacts very rapidly with azides.
Absorption and emission spectra of Cyanine7 fluorophore
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Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.EdU (5-Ethynyl-2'-deoxyuridine)
EdU is a nucleoside that is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by click chemistry reaction with fluorescent dye azides to reveal cell proliferation.General properties
| Appearance: | dark green solid |
| Mass spec M+ increment: | 849.5 |
| Molecular weight: | 885.62 |
| CAS number: | 2692677-77-1 |
| Molecular formula: | C58H65N4ClO2 |
| Solubility: | good in DMF, DMSO, DCM |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 199000 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.3 |
Product citations
- Park, J. S.; Lim, Y. G.; Park, K. Novel Bidentate β-Glutamic Acid-Based Bone-Targeting Agents for in Vivo Bone Imaging. Journal of Industrial and Engineering Chemistry, 2022, 110, 471–478. doi: 10.1016/j.jiec.2022.03.021
- Jäger, E.; Humajová, J.; Dölen, Y.; Kučka, J.; Jäger, A.; Konefał, R.; Pankrác, J.; Pavlova, E.; Heizer, T.; Šefc, L.; Hrubý, M.; Figdor, C. G.; Verdoes, M. Enhanced Antitumor Efficacy through an “AND Gate” Reactive Oxygen-Species-Dependent PH-Responsive Nanomedicine Approach. Advanced Healthcare Materials, 2021, 10(13), 2100304. doi: 10.1002/adhm.202100304
- Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
- Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574
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