DBCO-PEG6-NHS ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
3664-10mg | 10 mg | – | in stock | |
3664-50mg | 50 mg | $247 | in stock | |
3664-100mg | 100 mg | $449 | in stock | |
3664-1g | 1 g | $3490 | 5 days |
DBCO-PEG6-NHS ester is a bifunctional linker with dibenzocyclooctyne (DBCO) and NHS ester groups flanking PEG6 (hexaethylene glycol). The PEG spacer increases solubility in aqueous media and provides a long and flexible connection that minimizes steric hindrance involved with ligation.
Dibenzocyclooctyne readily reacts with azides via copper-free click chemistry reaction (strain-promoted alkyne azide cycloaddition, SPAAC). DBCO is one of the most reactive cycloalkynes that does not react with tetrazines.
The amine-reactive N-hydroxysuccinimide residue provides easy attachment to almost any primary or secondary amine group, such as protein, peptide, or small molecule amine.
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Appearance: | yellow to slightly orange oil |
Molecular weight: | 751.82 |
Molecular formula: | C39H49N3O12 |
Solubility: | DMSO, DMF, DCM, THF, Chloroform |
Quality control: | NMR 1H and HPLC-MS (95+%) |
Storage conditions: | 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |