FAM alkyne, 5-isomer
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
A41B0 | 1 mg | – | in stock | |
B41B0 | 5 mg | $100 | in stock | |
C41B0 | 10 mg | $150 | in stock | |
D41B0 | 25 mg | $295 | in stock | |
E41B0 | 50 mg | $450 | in stock | |
F41B0 | 100 mg | $780 | in stock |
FAM (fluorescein) alkyne for copper-catalyzed click chemistry, high purity (97+%) 5-isomer. The compound possesses significant aqueous solubility.
Absorbance and emission spectra of FAM
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Biotin-PEG4-alkyne
Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.FAM tetrazine, 6-isomer
This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).General properties
Appearance: | yellow solid |
Molecular weight: | 413.38 |
CAS number: | 510758-19-7 |
Molecular formula: | C24H15O6N |
Solubility: | good in aqueous buffers (pH > 8), alcohols, DMSO, DMF |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 492 |
ε, L⋅mol−1⋅cm−1: | 74000 |
Emission maximum, nm: | 517 |
Fluorescence quantum yield: | 0.93 |
CF260: | 0.22 |
CF280: | 0.17 |
Product citations
- Cardenas, A. J.; Thomas, K. S.; Broden, M. W.; Ferraro, N. J.; Pires, M. M.; John, C. M.; Jarvis, G. A.; Criss, A. K. Neisseria Gonorrhoeae Scavenges Host Sialic Acid for Siglec-Mediated, Complement-Independent Suppression of Neutrophil Activation. mBio, 2024, 15(5), e00119-24. doi: 10.1128/mbio.00119-24
- Wang, Y.-J.; Li, L.; Yu, J.; Hu, H.-Y.; Liu, Z.-X.; Jiang, W.-J.; Xu, W.; Guo, X.-P.; Wang, F.-S.; Sheng, J.-Z. Imaging of Escherichia Coli K5 and Glycosaminoglycan Precursors via Targeted Metabolic Labeling of Capsular Polysaccharides in Bacteria. Sci. Adv., 2023, 9(7), eade4770. doi: 10.1126/sciadv.ade4770
- Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
- Kamzabek, D.; Le Dé, B.; Coche-Guérente, L.; Miomandre, F.; Dubacheva, G.V. Thermoresponsive Fluorescence Switches Based on Au@pNIPAM Nanoparticles. Langmuir, 2021, 37(37), 10971–10978. doi: 10.1021/acs.langmuir.1c01397
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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