sulfo-Cyanine3.5 NHS ester

Cat. # Quantity Price Lead time
12320 1 mg $125 in stock
22320 5 mg $325 in stock
42320 25 mg $850 in stock
52320 50 mg $1490 in stock
62320 100 mg $1990 in stock
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Cyanine3.5 is a fluorescent dye with absorption and emission intermediate between Cyanine3 and Cyanine5. The sulfonated version contains four sulfo groups, which ensure high solubility and hydrophilicity of the fluorophore and labeled conjugates.

The NHS ester reactive group allows labeling of primary and secondary amine groups.

Absorption and emission spectra of sulfo-Cyanine3.5

Absorption and emission spectra of sulfo-Cyanine3.5

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sulfo-Cyanine5.5 amine

sulfo-Cyanine5.5 is a far-red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. This is an amine derivative that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling.

sulfo-Cyanine5 maleimide

Thiol reactive maleimide, water soluble cyanine dye for Cy5 channel.

ROX NHS ester, 6-isomer

Pure 6-isomer of ROX (Rhodamine X, R101) NHS-ester for amine labeling.
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General properties

Appearance: deep purple powder
Molecular weight: 1088.33
CAS number: 2231670-91-8 (without cation)
Molecular formula: C42H40N3K3O16S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 576
ε, L⋅mol−1⋅cm−1: 139000
Emission maximum, nm: 603
Fluorescence quantum yield: 0.11
CF260: 0.16
CF280: 0.17

Product citations

  1. McGuire, K.; He, S.; Gracie, J.; Bryson, C.; Zheng, D.; Clark, A.W.; Koehnke, J.; France, D.J.; Nau, W.M.; Lee, T.-C.; Peveler, W.J. Supramolecular Click Chemistry for Surface Modification of Quantum Dots Mediated by Cucurbit[7]uril. ACS nano, 2023, 17(21), 21585-21594. doi: 10.1021/acsnano.3c06601
  2. Shramova, E.; Proshkina, G.; Shipunova, V.; Ryabova, A.; Kamyshinsky, R.; Konevega, A.; Schulga, A.; Konovalova, E.; Telegin, G.; Deyev, S. Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape. Cancers, 2020, 12(10), 3014. doi: 10.3390/cancers12103014
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