sulfo-Cyanine5 DBCO
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 133F0 | 1 mg | $125 | in stock | |
| 233F0 | 5 mg | $325 | in stock | |
| 433F0 | 25 mg |
$850
|
in stock | |
| 533F0 | 50 mg |
$1490
|
in stock | |
| 633F0 | 100 mg |
$1990
|
in stock |
Copper-free click chemistry reaction between strained cycloalkynes (cyclooctynes) and azides is a very fast and robust reaction. It can be used for fast labeling with fluorescent dyes. This reagent is a derivative of water-soluble sulfo-Cyanine5 dye, which emits in a red channel. It is useful for the labeling of biomolecules in aqueous media.
Absorption and emission spectra of sulfo-Cyanine5
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6-Carboxy-H2DCFDA (6-carboxy-2',7'-dichlorodihydrofluorescein)
A reagent for detecting reactive oxygen species (ROS) in living cells. This carboxylated H2DCFDA analog has two additional negative charges that impede its leakage out of the cell.sulfo-Cyanine7 carboxylic acid
sulfo-Cyanine7 carboxylic acid is a non-reactive fluorescent dye that can be used as a NIR (near-infrared) marker.Azide-PEG3-amine
A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)General properties
| Appearance: | dark colored solid |
| Molecular weight: | 981.27 |
| Molecular formula: | C53H57N4KO8S2 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 646 |
| ε, L⋅mol−1⋅cm−1: | 271000 |
| Emission maximum, nm: | 662 |
| Fluorescence quantum yield: | 0.28 |
Product citations
- Hebels, E. R.; Bindt, F.; Walther, J.; van Geijn, M.; Weterings, J.; Hu, Q.; Colombo, C.; Liskamp, R.; Rijcken, C.; Hennink, W. E.; Vermonden, T. Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation. Biomacromolecules, 2023, 24(10), 4385–4396. doi: 10.1021/acs.biomac.2c00865
- Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425
- Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
- Pontes, A.P.; van der Wal, S.; Ranamalla, S.R.; Roelofs, K.; Tomuta, I.; Creemers, L.B.; Rip, J. Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation in chondrocytes. Frontiers in Bioengineering and Biotechnology, 2023, 11, 1290871. doi: 10.3389/fbioe.2023.1290871
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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