Alkyne-PEG3-carboxylic acid
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1743-1g | 1 g |
$490
|
in stock | |
| 1743-5g | 5 g |
$980
|
in stock | |
| 1743-25g | 25 g | please inquire | in stock |
Alkyne-PEG3-carboxylic acid is a bifunctional triethyleneglycol derivative bearing a carboxy group and an alkyne moiety. The former can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. The alkyne group can be coupled with azides in a CuAAC reaction.
PEGs are hydrophilic linkers useful in synthesizing water-soluble conjugates.
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General properties
| Appearance: | colorless to yellow oil |
| Molecular weight: | 246.26 |
| CAS number: | 1415800-32-6 |
| Molecular formula: | C11H18O6 |
| IUPAC name: | 3,6,9,12-tetraoxapentadecyn-15-oic acid |
| Solubility: | good in most organic solvents and water |
| Quality control: | NMR 1H, GC-MS (95%, as Me ester) |
| Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product citations
- Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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