Azide-PEG4-amine

Azides Amines Click chemistry Crosslinking
Cat. # Quantity Price Lead time
1868-1g 1 g $90 in stock
1868-5g 5 g $250 in stock
1868-25g 25 g please inquire in stock
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Oligoethylene glycols are versatile hydrophilic linkers. Each monomer has a length of 3.43 Å, so the length of PEG4 is around 14 Å (1.4 nm).

Azide-PEG4-amine is a bifunctional compound with an amine group that can be modified by acylation by activated esters or similar carbonyl compounds and an azide group that is suitable for click chemistry reactions. PEG4 is highly hydrophilic and biocompatible.

Azide-PEG4-Amine, 1868-1g
Azide-PEG4-Amine, 1868-1g
Azide-PEG4-Amine, 1868-1g
Structure of Azide-PEG4-Amine (CAS# 134179-38-7)
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THPTA ligand

THPTA is a water-soluble ligand for Cu(I)-catalyzed click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

Alkyne-PEG4-amine

A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

General properties

Appearance: colorless to yellowish liquid
Molecular weight: 218.25
CAS number: 134179-38-7
Molecular formula: C8H18N4O3
Solubility: miscible with water, polar organic solvents
Quality control: NMR 1H,GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Moody, C.T.; Brown, A.E.; Massaro, N.P.; Patel, A.S.; Agarwalla, P.A.; Simpson, A.M.; Brown, A.C.; Zheng, H.; Pierce, J.G.; Brudno, Y. Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture. Acta Biomaterialia, 2022, 138, 208-217. doi: 10.1016/j.actbio.2021.10.046
  2. Moody, C.T.; Palvai, S.; Brudno, Y. Click Cross-linking Improves Retention and Targeting of Refillable Alginate Depots. Acta Biomaterialia, 2020, 112, 112-121. doi: 10.1016/j.actbio.2020.05.033
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