sulfo-Cyanine5 carboxylic acid

Cat. # Quantity Price Lead time
13390 1 mg $115 in stock
23390 5 mg $240 in stock
43390 25 mg $510 in stock
53390 50 mg $895 in stock
63390 100 mg $1390 in stock
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Non-activated sulfo-Cyanine5 carboxylic acid, water soluble dye. This dye is highly hydrophilic and water-soluble. Non-sulfonated analog is available.

The fluorophore is an equivalent of Cy5® carboxylic acid.

For labeling applications consider using pre-activated sulfo-Cy5 NHS ester

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 absorbance and emission spectra

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Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cyanine3 carboxylic acid

The free carboxylic acid of Cyanine3 dye. Non-sulfonated dye, with good solubility in organic solvents, and limited aqueous solubility.

General properties

Appearance: dark blue powder
Molecular weight: 680,87
CAS number: 1144107-82-3 (potassium salt), 1121756-16-8 (inner salt), 2098639-31-5 (sodium salt)
Molecular formula: C32H37N2KO8S2
Solubility: Well soluble in water, DMF, DMSO (0.35 M = 240 g/L). Practically insoluble in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Comeo, E.; Goulding, J.; Lin, C.-Y.; Groenen, M.; Woolard, J.; Kindon, N. D.; Harwood, C. R.; Platt, S.; Briddon, S. J.; Kilpatrick, L. E.; Scammells, P. J.; Hill, S. J.; Kellam, B. Ligand-Directed Labeling of the Adenosine A1 Receptor in Living Cells. J. Med. Chem., 2024, 67(14), 12099–12117. doi: 10.1021/acs.jmedchem.4c00835
  2. Ji, Y.; Chakraborty, T.; Wegner, S. V. Self-Regulated and Bidirectional Communication in Synthetic Cell Communities. ACS Nano, 2023, 17(10), 8992–9002. doi: 10.1021/acsnano.2c09908
  3. Dirscherl, C. F.; Ianeselli, A.; Tetiker, D.; Matreux, T.; Queener, R. M.; Mast, C. B.; Braun, D. A Heated Rock Crack Captures and Polymerizes Primordial DNA and RNA. Phys. Chem. Chem. Phys., 2023, 25(4), 3375–3386. doi: 10.1039/D2CP04538A
  4. Li, S.; Co, C. M.; Izuagbe, S.; Hong, Y.; Liao, J.; Borrelli Jr., J.; Tang, L. Biomolecules-Releasing Click Chemistry-Based Bioadhesives for Repairing Acetabular Labrum Tears. Journal of Orthopaedic Research, 2022, 40(11), 2646–2655. doi: 10.1002/jor.25290
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