Disuccinimidyl glutarate (DSG)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 4018-100mg | 100 mg | $95 | in stock | |
| 4018-1g | 1 g |
$410
|
in stock |
Disuccinimidyl glutarate (DSG) is a homobifunctional crosslinker that contains two N-hydroxysuccinimide (NHS) ester groups at each end of a short 5-atom (7.7 angstrom) spacer.
DSG is a membrane-permeable and non-cleavable crosslinker, allowing for intracellular labeling of peptides and proteins. NHS esters react with amines of lysine residues and N-termini of peptides and proteins, forming a covalent amide bond and releasing the NHS group. DSG is commonly used to pair radiolabelled ligands to cell surface receptors and determine DNA-protein binding interactions in ChIP assays. DSG labeling is often combined with formaldehyde fixation to improve the detection of DNA-protein complexes.
DSG is water-insoluble and must be dissolved in an organic solvent, such as DMSO or DMF, before being added to aqueous solutions.
Recommended protocol
Calculator
Customers also purchased with this product
Cyanine5 azide
Cyanine5 azide is a reagent for click chemistry labeling with Cyanine5, a popular fluorescent dye.
Add this product to your cart andget free express delivery
Cyanine5 DBCO
Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper-free click chemistry.AF 488 azide
AF 488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.General properties
| Appearance: | off-white powder |
| Molecular weight: | 326.26 |
| CAS number: | 79642-50-5 |
| Molecular formula: | C13H14N2O8 |
| IUPAC name: | Bis(2,5-dioxopyrrolidin-1-yl) Pentanedioate |
| Solubility: | DMF, DMSO |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Your cart is empty
$ 
