Phosphate CPG 500 solid support

CPG modifier solid supports
Cat. # Quantity Price Lead time
13860 100 mg $40 in stock
43860 1 g $170 in stock
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Phosphate CPG is a solid support for the synthesis of 3'-phosphorylated oligonucleotides. The phosphate group can be used as a blocking functionality to prevent 3'-5' exonuclease activity of some polymerases.

Upon cleavage from the support, a phosphate group remains at the 3' end of the oligonucleotide. It does not require any changes in oligo synthesis and deprotection protocols.

Phosphate CPG 500 solid support, 43860
Phosphate CPG 500 solid support, 43860
Phosphate CPG 500 solid support, 43860
Structure of phosphate CPG 500 solid support
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General properties

Appearance: off-white beads
Quality control: NMR 1H, HPLC-MS (95%) of bound reagent, loading measurement, functional testing (oligo synthesis)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50−80
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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