Cyanine3 amine

Cyanine3 Amines
Cat. # Quantity Price Lead time
110C0 1 mg $125 5 days
210C0 5 mg $260 in stock
410C0 25 mg $510 in stock
510C0 50 mg $895 in stock
610C0 100 mg $1490 in stock
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Cyanine3 amine is a functionalized cyanine dye containing a free amino group. Cyanine3 is an analog of Cy3®.

Amino group of this reagent can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.

The amino dye is supplied in salt form, and possesses some aqueous solubility.

Cyanine3 amine, 510C0
Cyanine3 amine, 510C0
Cyanine3 amine, 510C0
Cyanine3 amine structure
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Cyanine3 absorption and emission spectra

Cyanine3 absorption and emission spectra

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General properties

Appearance: red powder
Molecular weight: 627.73
CAS number: 2247688-56-6
Molecular formula: C36H52Cl2N4O
IUPAC name: 3H-​Indolium, 1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​2-​[3-​(1,​3-​dihydro-​1,​3,​3-​trimethyl-​2H-​indol-​2-​ylidene)​-​1-​propen-​1-​yl]​-​3,​3-​dimethyl-​, chloride, hydrochloride (1:1:1)
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

Product citations

  1. Kovshova, T.; Malinovskaya, J.; Kotova, J.; Gorshkova, M.; Vanchugova, L.; Osipova, N.; Melnikov, P.; Vadekhina, V.; Nikitin, A.; Ermolenko, Y.; Gelperina, S. Core–Shell PLGA Nanoparticles: In Vitro Evaluation of System Integrity. Biomolecules, 2024, 14(12), 1601. doi: 10.3390/biom14121601
  2. Gorshkova, M.; Vanchugova, L.; Osipova, N.; Nikitin, A.; Kotova, J.; Kovalenko, E.; Ermolenko, Y.; Malinovskaya, J.; Kovshova, T.; Gelperina, S. Hybrid DIVEMA/PLGA nanoparticles as the potential drug delivery system. Research Square, 2024, preprint. doi: 10.21203/rs.3.rs-4594368/v1
  3. Lee, J.-R.; Sim, W.-S.; Park, H.-J.; Park, B.-W.; Joung, Y. K. Targeted Delivery of Apoptotic Cell-Derived Nanovesicles Prevents Cardiac Remodeling and Attenuates Cardiac Function Exacerbation. Advanced Functional Materials, 2023, 33(23), 2210864. doi: 10.1002/adfm.202210864
  4. Ruan, Z.; Li, S.; Grigoropoulos, A.; Amiri, H.; Hilburg, S. L.; Chen, H.; Jayapurna, I.; Jiang, T.; Gu, Z.; Alexander-Katz, A.; Bustamante, C.; Huang, H.; Xu, T. Population-Based Heteropolymer Design to Mimic Protein Mixtures. Nature, 2023, 615(7951), 251–258. doi: 10.1038/s41586-022-05675-0
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Cy® is a trademark of GE Healthcare.
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