sulfo-Cyanine5.5 maleimide

sulfo-Cyanine5.5 Maleimides
Cat. # Quantity Price Lead time
17380 1 mg $125 in stock
27380 5 mg $325 in stock
47380 25 mg $790 in stock
57380 50 mg $1490 in stock
67380 100 mg $1990 in stock
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sulfo-Cyanine5.5 dye is a water-soluble far-red to NIR emitting dye that is very hydrophilic due to the presence of four sulfo groups. sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is perfect for labeling sensitive proteins, nanoparticles, and highly hydrophilic biopolymers.

This maleimide is a thiol-reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

Sulfo-Cyanine5.5 maleimide, 67380
Sulfo-Cyanine5.5 maleimide, 67380
Sulfo-Cyanine5.5 maleimide, 67380
Structure of Sulfo-Cyanine5.5 maleimide
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Absorption and emission spectra of sulfo-Cyanine5.5

Absorption and emission spectra of sulfo-Cyanine5.5

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Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

sulfo-Cyanine3.5 NHS ester

Amine-reactive activated ester of water-soluble, sulfonated sulfo-Cyanine3.5 dye.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 1024.2
Molecular weight: 1139.43
CAS number: 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula: C46H45K3N4O15S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

Product citations

  1. Bayon, J.L.; Shih, C.; Craig, S.L.; Steinmetz, N.F. A simple swell-and-click method for the covalent attachment of virus-like particles to polymer hydrogels. Materials Today Chemistry, 2024, 38, 102100. doi: 10.1016/j.mtchem.2024.102100
  2. Sabuncu, S.; Montoya Mira, J.; Quentel, A.; Gomes, M. M.; Civitci, F.; Fischer, J. M.; Yildirim, A. Protein-Coated Biodegradable Gas-Stabilizing Nanoparticles for Cancer Therapy and Diagnosis Using Focused Ultrasound. Advanced Materials Interfaces, 2023, 10(2), 2201543. doi: 10.1002/admi.202201543
  3. Das, S.K.; Huynh, M.T.; Lee, T.-H. Spontaneous histone exchange between nucleosomes. The Journal of Biological Chemistry, 2023, 299(8), 105037. doi: 10.1016/j.jbc.2023.105037
  4. Çetin, B.; O’Leary, S.E. mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation. Nucleic Acids Research, 2022, 50(14), 8240-8261. doi: 10.1093/nar/gkac631
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