sulfo-Cyanine5.5 maleimide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 17380 | 1 mg | $125 | in stock | |
| 27380 | 5 mg | $325 | in stock | |
| 47380 | 25 mg |
$790
|
in stock | |
| 57380 | 50 mg |
$1490
|
in stock | |
| 67380 | 100 mg |
$1990
|
in stock |
sulfo-Cyanine5.5 dye is a water-soluble far-red to NIR emitting dye that is very hydrophilic due to the presence of four sulfo groups. sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is perfect for labeling sensitive proteins, nanoparticles, and highly hydrophilic biopolymers.
This maleimide is a thiol-reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.
Absorption and emission spectra of sulfo-Cyanine5.5
Recommended protocol
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sulfo-Cyanine7.5 NHS ester
A water-soluble near-infrared emitting dye for in vivo imaging applications. sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield and a linker arm.Azide-PEG6-NHS ester
A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).
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Indocyanine Green (ICG)
Water-soluble and pH-insensitive fluorescent dye widely used in imaging and flow cytometry.General properties
| Appearance: | dark colored solid |
| Mass spec M+ increment: | 1024.2 |
| Molecular weight: | 1139.43 |
| CAS number: | 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt) |
| Molecular formula: | C46H45K3N4O15S4 |
| Solubility: | good in water, DMSO, DMF |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 673 |
| ε, L⋅mol−1⋅cm−1: | 211000 |
| Emission maximum, nm: | 691 |
| Fluorescence quantum yield: | 0.21 |
| CF260: | 0.09 |
| CF280: | 0.11 |
Product citations
- Bayon, J.L.; Shih, C.; Craig, S.L.; Steinmetz, N.F. A simple swell-and-click method for the covalent attachment of virus-like particles to polymer hydrogels. Materials Today Chemistry, 2024, 38, 102100. doi: 10.1016/j.mtchem.2024.102100
- Sabuncu, S.; Montoya Mira, J.; Quentel, A.; Gomes, M. M.; Civitci, F.; Fischer, J. M.; Yildirim, A. Protein-Coated Biodegradable Gas-Stabilizing Nanoparticles for Cancer Therapy and Diagnosis Using Focused Ultrasound. Advanced Materials Interfaces, 2023, 10(2), 2201543. doi: 10.1002/admi.202201543
- Das, S.K.; Huynh, M.T.; Lee, T.-H. Spontaneous histone exchange between nucleosomes. The Journal of Biological Chemistry, 2023, 299(8), 105037. doi: 10.1016/j.jbc.2023.105037
- Çetin, B.; O’Leary, S.E. mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation. Nucleic Acids Research, 2022, 50(14), 8240-8261. doi: 10.1093/nar/gkac631
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