Ac4GalNAl (N-(4-pentynoyl)-galactosamine-tetraacylated)

Cat. # Quantity Price Lead time
4037-5mg 5 mg $129 in stock
4037-25mg 25 mg $240 in stock
4037-100mg 100 mg $630 in stock
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The tetraacetylated N-(4-pentynoyl)-galactosamine (Ac4GalNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GalNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylgalactosamine (GalNAc).

The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.

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General properties

Appearance: white solid
Molecular weight: 427.40
CAS number: 1658458-26-4
Molecular formula: C19H25NO10
IUPAC name: 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(4-pentynoylamino)-α-D-galactopyranose
Solubility: DMSO, DMF, DCM, THF, chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
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