Alkyne dT phosphoramidite
This product is discontinued, and no longer available.
We recommend Alkyne dT phosphoramidite as a substitute
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This product will be discontinued soon in favor of Alkyne dT phosphoramidite. We may still have some material in stock (please see availability above).
Alkyne dT phosphoramidite is used for the synthesis of oligonucleotides containing an internal alkyne modification attached to the uridine 5-position. The alkyne group can be subsequently modified by various azides using copper-catalyzed Click chemistry.
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General properties
| Appearance: | white solid |
| Molecular weight: | 935.01 |
| Molecular formula: | C50H59N6O10P |
| Solubility: | good in THF, DCM, acetonitrile |
| Quality control: | NMR 1H, HPLC-MS (90+%), functional testing in oligo synthesis |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Coupling conditions: | 6 min. coupling time; 45 sec. oxidation time |
| Cleavage conditions: | ammonia, 2 h at room temperature |
| Deprotection conditions: | identical to protected nucleobases |
Short link - lumiprobe.com/sh/p/2p
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