FAM phosphoramidite, 5-isomer
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
2639-500mg
/ Easily soluble lyophilised form in 8 mL septum
|
500 mg | – | in stock | |
2639-1g
/ Easily soluble lyophilised form in 20 mL septum
|
1 g |
$190
|
in stock | |
2639-5g
/ in 30 mL septum
|
5 g |
$740
|
in stock | |
2639-10g
/ in 30 mL septum
|
10 g |
$1290
|
in stock | |
2639-50g | 50 g | please inquire | 21 days | |
2639-100g | 100 g | please inquire | 21 days |
Delivery dates and prices will be calculated based on your ZIP
Items in stock will be shipped on
04/02/2025
Free express shipping from
$400!
Add products for
$400
to your cart and get free express shipping .
No handling fees!
Standard fluorescein (FAM) phosphoramidite for 5'-terminal oligonucleotide labeling, high isomeric purity single isomer. This highly purified amidite reagent ensures excellent coupling results with various synthesizers.
Samples and special offers are available for oligo manufacturers. Contact us for bulk supplies of this reagent.
FAM absorbance and emission spectra

Customers also purchased with this product
TAMRA phosphoramidite, 5-isomer
TAMRA phosphoramidite for synthesis of 5’-labeled oligonucleotides. Pure 5-isomer.get free express delivery
FAM CPG 500, 6-isomer
Controlled pore glass for the synthesis of modified oligonucleotides containing 3'-fluorescein (FAM) modification.get free express delivery
Ascorbic acid
Ascorbic acid is a reducing agent converting copper(II) into a monovalent form that catalyzes the click reaction.General properties
Appearance: | off white solid |
Molecular weight: | 843.94 |
CAS number: | 147566-42-5 |
Molecular formula: | C46H58N3O10P |
Solubility: | Good solubility in acetonitrile and DCM |
Quality control: | NMR 1H and 31P, HPLC-MS (95+%), isomeric purity > 97% |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 492 |
ε, L⋅mol−1⋅cm−1: | 72000 |
Emission maximum, nm: | 517 |
Fluorescence quantum yield: | 0.93 |
CF260: | 0.22 |
CF280: | 0.17 |
Oligo synthesis details
Diluent: | acetonitrile |
Coupling conditions: | coupling time 10 min |
Cleavage conditions: | ammonia, 2 h at room temperature |
Deprotection conditions: | identical to protected nucleobases; when AMA is used, deblock with ammonia alone for 30 min, then add methylamine |
Product citations
- Zharkov, T. D.; Markov, O. V.; Zhukov, S. A.; Khodyreva, S. N.; Kupryushkin, M. S. Influence of Combinations of Lipophilic and Phosphate Backbone Modifications on Cellular Uptake of Modified Oligonucleotides. Molecules, 2024, 29(2), 452. doi: 10.3390/molecules29020452
- Bauer, I.; Ilina, E.; Zharkov, T.; Grigorieva, E.; Chinak, O.; Kupryushkin, M.; Golyshev, V.; Mitin, D.; Chubarov, A.; Khodyreva, S.; Dmitrienko, E. Self-Penetrating Oligonucleotide Derivatives: Features of Self-Assembly and Interactions with Serum and Intracellular Proteins. Pharmaceutics, 2023, 15(12), 2779. doi: 10.3390/pharmaceutics15122779
- Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
Short link - lumiprobe.com/sh/p/7z
The count of items is incorrect.
