Cyanine5.5 maleimide

Cyanine5.5 Maleimides

Cat. #	Quantity	Price	Lead time
17080	1 mg	$125	in stock
27080	5 mg	$260	in stock
47080	25 mg	$510	in stock
57080	50 mg	$895	in stock
67080	100 mg	$1490	in stock

Found better price? Let us know and we will propose the way forward!

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5® and DyLight 680.

Download in
ChemDraw format

Cyanine5.5 absorbance and emission spectra

Recommended protocol

Maleimide Labeling of Proteins and Other Thiolated Biomolecules

Calculator

Solution calculator

Customers also purchased with this product

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide is a carbonyl reactive NIR dye which is particularly suitable for the labeling of periodate oxidized glycoproteins, i.e. antibodies.

AF 343 (Coumarin) is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

Cyanine7 carboxylic acid

The unactivated free carboxylic acid of near-infrared fluorescent dye Cyanine7.

General properties

Appearance:	dark blue powder
Molecular weight:	850.89
CAS number:	1593644-50-8
Molecular formula:	C₄₆H₄₉F₆N₄O₃P
IUPAC name:	1H-Benz[e]indolium, 2-[5-[3-[6-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-6-oxohexyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-1,1,3-trimethyl-
Solubility:	soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	684
ε, L⋅mol⁻¹⋅cm⁻¹:	198000
Emission maximum, nm:	710
Fluorescence quantum yield:	0.2
CF₂₆₀:	0.07
CF₂₈₀:	0.03

Product citations

Kumar Podder, A.; Mohamed, M.A.; Seidman, R.A.; Tseropoulos, G.; Polanco, J.J.; Lei, P.; Sim, F.J.; Andreadis, S.T. Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system. Science Advances, 2024, 10(28), eadk9918. doi: 10.1126/sciadv.adk9918
Huang, S.; Gao, Y.; Ma, L.; Jia, B.; Zhao, W.; Yao, Y.; Li, W.; Lin, T.; Wang, R.; Song, J.; Zhang, W. Design of pH-responsive antimicrobial peptide melittin analog-camptothecin conjugates for tumor therapy. Asian Journal of Pharmaceutical Sciences, 2024, 19(1), 100890. doi: 10.1016/j.ajps.2024.100890
Prabhakar, A.; Pavlov, M. Y.; Zhang, J.; Indrisiunaite, G.; Wang, J.; Lawson, M. R.; Ehrenberg, M.; Puglisi, J. D. Dynamics of Release Factor Recycling during Translation Termination in Bacteria. Nucleic Acids Research, 2023, 52(11), 5774–5790. doi: 10.1093/nar/gkad286
De Rosa, L.; Hawala, I.; Di Stasi, R.; Stefania, R.; Capozza, M.; Nava, D.; D’Andrea, L. D. A Chemical Strategy for the Preparation of Multimodified Peptide Imaging Probes. J Org Chem, 2023, 88(7), 4546–4553. doi: 10.1021/acs.joc.3c00014

Show more (21)

Cy® is a trademark of Cytiva.

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.