F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
3438-5mg | 5 mg | – | in stock | |
3438-25mg | 25 mg | $375 | in stock | |
3438-100mg | 100 mg | $825 | in stock | |
3438-500mg | 500 mg | please inquire | in stock |
F-ara-EdU (2’-deoxy-2’-fluoro-5-ethynyluridine) is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU (5-Bromo-2’-deoxyuridine) and EdU (5-Ethynyl-2’-deoxyuridine).
F-ara-EdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. Metabolic incorporation of F-ara-EdU into DNA can be detected by copper-catalyzed click reaction with fluorescent or biotin-labeled azides.
In contrast to EdU, F-ara-EdU causes little or no cellular arrest or DNA synthesis inhibition. Therefore, F-ara-EdU is ideally suited for pulse-chase experiments aimed at birth-dating DNA in vivo and long-term cell survival estimation.
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Appearance: | off-white powder |
Molecular weight: | 270.22 |
CAS number: | 95740-26-4 |
Molecular formula: | C11H11FN2O5 |
Solubility: | in water, DMSO, DMF |
Quality control: | NMR 1H and HPLC-MS (95+%) |
Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |