sulfo-Cyanine3 tetrazine

Cat. # Quantity Price Lead time
113E0 1 mg $125 in stock
213E0 5 mg $325 in stock
313E0 10 mg $470 in stock
413E0 25 mg $850 in stock
513E0 50 mg $1490 in stock
613E0 100 mg $1990 in stock
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Tetrazine-trans-cyclooctene ligation is among the fastest bioconjugation reactions known to date.

This water-soluble sulfo-Cyanine3 derivative contains methyltetrazine moiety for the coupling with trans-cyclooctenes. Methyltetrazines possess optimal stability at physiological pH, while maintaining extremely high reactivity towards cyclooctenes.

The fluorophore is bright, photostable, and is also very well visible with naked eye.

Absorption and emission spectra of Cyanine3

Absorption and emission spectra of Cyanine3

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General properties

Appearance: red powder
Molecular weight: 838.05
Molecular formula: C40H44KN7O7S2
IUPAC name: Potassium (E)-2-[(E)-3-{3,3-Dimethyl-1-[6-({[p-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl}amino)-6-oxohexyl]-5-(oxysulfonyl)-3H-indol-2-yl}-2-propenylidene]-1-methyl-3,3-dimethyl-5-indolinesulfonate
Solubility: soluble in water (0.43 M = 36 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
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