sulfo-Cyanine5.5 carboxylic acid

Cat. # Quantity Price Lead time
17390 1 mg $125 in stock
27390 5 mg $325 in stock
47390 25 mg $850 in stock
57390 50 mg $1490 in stock
67390 100 mg $1990 in stock
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sulfo-Cyanine5.5 (analog of Cy5.5®) is a water-soluble, far-red emitting fluorophore. Due to four sulfo groups, the dye possesses a negative charge in neutral pH, and very high hydrophilicity. As a cyanine dye, sulfo-Cyanine5.5 shows a very low dependence of the fluorescence on pH, and a very high extinction coefficient.

This product is a free non-activated carboxylic acid that can be used for calibration and as a non-reactive control.

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 absorption and emission spectra

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sulfo-Cyanine5.5 azide

sulfo-Cyanine5.5 azide is a derivative of water-soluble far-red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper-free click chemistry with alkynes and cycloalkynes.

EDC (N-ethyl-N'-(3-dimethylaminopropyl)carbodiimide), coupling grade

Water soluble carbodiimide for the coupling of carboxylic acids with amines.

sulfo-Cyanine7.5 dicarboxylic acid

sulfo-Cyanine7.5 dicarboxylic acid is a bifunctional cyanine dye with two carboxylic acid (COOH) groups. The molecule can be used to construct cross conjugates containing a near-infrared emitting fluorophore.

General properties

Appearance: dark blue solid
Molecular weight: 1017.31
CAS number: 2183440-68-6 (inner salt)
Molecular formula: C40H39K3N2O14S4
Solubility: Well soluble in water, DMF, DMSO (0.39 M = 400 g/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

Product citations

  1. Shik, A. V.; Sobolev, P. V.; Zubritskaya, Y. V.; Baytler, M. O.; Stepanova, I. A.; Chernyaev, A. P.; Borschegovskaya, P. Yu.; Zolotov, S. A.; Doroshenko, I. A.; Podrugina, T. A.; Bliznyuk, U. A.; Rodin, I. A.; Beklemishev, M. K. Rapid Testing of Irradiation Dose in Beef and Potatoes by Reaction-Based Optical Sensing Technique. Journal of Food Composition and Analysis, 2024, 127, 105946. doi: 10.1016/j.jfca.2023.105946
  2. Ko, H. S.; Yang, D. H.; Kim, A.; Wie, J. H.; Kim, S. H.; Jeong, G.-J.; Hyun, H.; Shin, J. C.; Chun, H. J. Visible Light-Curable Methacrylated Glycol Chitosan Hydrogel Patches for Prenatal Closure of Fetal Myelomeningocele. Carbohydrate Polymers, 2023, 311, 120620. doi: 10.1016/j.carbpol.2023.120620
  3. Park, J. Y.; You, S. J.; Park, K.; Song, Y. J.; Park, J. S.; Yang, D. H.; Kim, J. K.; Chun, H. J.; Khang, G. Cyclic RGDfK- and Sulfo-Cy5.5-Functionalized MPEG-PCL Theranostic Nanosystems for Hepatocellular Carcinoma. Journal of Industrial and Engineering Chemistry, 2021, 99, 204–213. doi: 10.1016/j.jiec.2021.04.023
  4. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
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