Copper(II)-BTTAA complex
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 10050 | 1 mL | $80 | in stock |
Copper(II)-BTTAA complex is a component of our recommended catalyst for conjugating azides with alkynes using a copper-catalyzed click reaction (CuAAC) in an aqueous medium. This complex is stable and contains divalent copper in the form of 10 mM CuSO4 in an aqueous solution of BTTAA. When Cu(II)-BTTAA is treated with reducing agents, such as ascorbic acid, a catalytically active complex with monovalent copper(I) is formed.
BTTAA maintains the catalyst’s oxidation state of Cu(I) and protects biomolecules from oxidative damage during labeling. BTTAA also significantly reduces the click reaction’s cellular cytotoxicity by reducing the copper content in the catalyst.
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An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.BTTAA ligand
BTTAA is the newest generation of water-soluble ligands for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity.General properties
| Appearance: | light blue solution |
| Solubility: | good in water |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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