sulfo-Cyanine7 NHS ester

Cat. # Quantity Price Lead time
15320 1 mg
$119.90
in stock
25320 5 mg
$209.90
in stock
45320 25 mg
$599.90
in stock
55320 50 mg
$999.00
in stock
65320 100 mg
$1599.00
in stock
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Water-soluble near-infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.

sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.

Near-infrared fluorescent imaging takes advantage of the transparency of biological tissues at a particular range of wavelengths. The method is non-destructive and allows to monitor of the distribution of various labeled molecules in live organisms.

sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye-labeled molecules can be subsequently used for various research and drug design-related experiments.

This reagent has high water solubility and is especially useful for labeling delicate proteins and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in the organic phase is also available.

Absorption and emission spectra of sulfo-Cyanine7

Absorption and emission spectra of sulfo-Cyanine7

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General properties

Appearance: dark green powder
Molecular weight: 844.05
CAS number: 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt)
Molecular formula: C41H46N3KO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

Product citations

  1. White, M. J. V.; Raczy, M. M.; Budina, E.; Yuba, E.; Solanki, A.; Shim, H.-N.; Zhang, Z. J.; Gray, L. T.; Cao, S.; Alpar, A. T.; Hubbell, J. A. Engineering IL-10 and Rapamycin to Bind Collagen Leads to Improved Anti Fibrotic Efficacy in Lung and Kidney Fibrosis. Sci Rep, 2025, 15(1), 13279. doi: 10.1038/s41598-025-94073-3
  2. Morath, V.; Maurer, S.; Feuchtinger, A.; Walser, R.; Schlapschy, M.; Bolze, F.; Metzler, T.; Bruder, J.; Steiger, K.; Walch, A.; Klingenspor, M.; Skerra, A. Long-Acting Human PASylated Leptin Reaches the Murine Central Nervous System and Offers Potential for Optimized Replacement Therapy. Mol. Pharmaceutics, 2025, 22(6), 3017–3032. doi: 10.1021/acs.molpharmaceut.4c01503
  3. Saunders, R. A.; Allen, W. E.; Pan, X.; Sandhu, J.; Lu, J.; Lau, T. K.; Smolyar, K.; Sullivan, Z. A.; Dulac, C.; Weissman, J. S.; Zhuang, X. Perturb-Multimodal: A Platform for Pooled Genetic Screens with Imaging and Sequencing in Intact Mammalian Tissue. Cell, 2025, 188(17), 4790-4809.e22. doi: 10.1016/j.cell.2025.05.022
  4. Leng, F.; Merino-Urteaga, R.; Wang, X.; Zhang, W.; Ha, T.; Hur, S. Ultrastable and Versatile Multimeric Ensembles of FoxP3 on Microsatellites. Molecular Cell, 2025, 85(8), 1509-1524.e7. doi: 10.1016/j.molcel.2025.03.005
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