Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
4130-5mg | 5 mg | $129 | in stock | |
4130-25mg | 25 mg | $240 | in stock | |
4130-100mg | 100 mg | $630 | in stock |
The tetraacetylated N-(4-pentynoyl)-glucosamine (Ac4GlcNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.
Ac4GlcNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylglucosamine (GlcNAc).
The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.
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An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.General properties
Appearance: | beige powder |
Molecular weight: | 427.41 |
CAS number: | 1361993-37-4 |
Molecular formula: | C19H25NO10 |
IUPAC name: | 2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-2-deoxy-1,3,4,6-tetra-O-acetyl-D-glucopyranose |
Solubility: | DMSO, DMF, DCM, THF, chloroform |
Quality control: | NMR 1H and HPLC-MS (95+%) |
Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |